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α-D-Galactopyranosylphenyl isothiocyanate

Catalog No.GC40702

α-D-Galactopyranosylphenyl isothiocyanate is a chemically activated form of galactose that has been used to prepare various neoglycoproteins, which consist of a glycosylated serum albumin substituted with either fluorescein or methotrexate.

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α-D-Galactopyranosylphenyl isothiocyanate Chemical Structure

Cas No.: 120967-92-2

Taille Prix Stock Qté
500μg
43,00 $US
En stock
1mg
82,00 $US
En stock
5mg
283,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

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Product Documents

Quality Control & SDS

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Background

α-D-Galactopyranosylphenyl isothiocyanate is a chemically activated form of galactose that has been used to prepare various neoglycoproteins, which consist of a glycosylated serum albumin substituted with either fluorescein or methotrexate.[1]  Neoglycoproteins are used to identify the presence and sugar specificity of membrane lectins on the cell surface of mouse L1210 leukemia cells and to study membrane lectin-mediated endocytosis.

References
[1]. Monsigny, M., Roche, A.C., and Midoux, P. Uptake of neoglycoproteins via membrane lectin(s) of L1210 cells evidenced by quantitative flow cytofluorometry and drug targeting. Biol.Cell 51(2), 187-196 (1984).

Chemical Properties

Cas No. 120967-92-2 SDF
Chemical Name α-D-galactopyranoside, isothiocyanatophenyl
Canonical SMILES S=C=NC(C=C1)=CC=C1O[C@@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O2
Formula C13H15NO6S M.Wt 313.3
Solubility 20mg/mL in DMSO, 30mg/mL in DMF Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 3.1918 mL 15.9591 mL 31.9183 mL
5 mM 0.6384 mL 3.1918 mL 6.3837 mL
10 mM 0.3192 mL 1.5959 mL 3.1918 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Review for α-D-Galactopyranosylphenyl isothiocyanate

Average Rating: 5 ★★★★★ (Based on Reviews and 26 reference(s) in Google Scholar.)

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