α-Tocopherol phosphate disodium (Synonyms: alpha-Tocopherol phosphate disodium; TocP disodium; Vitamin E phosphate disodium) |
| Catalog No.GC67618 |
α-Le phosphate de tocophérol (phosphate d'alpha-tocophérol) disodique, un antioxydant prometteur, peut protéger contre la mort cellulaire induite par les UVA1 à ondes longues et piéger les ROS induites par les UVA1 dans un modèle de cellule cutanée. α ; - Le phosphate de tocophérol disodique possède un potentiel thérapeutique dans l'inhibition de l'apoptose et augmente la capacité migratoire des cellules progénitrices endothéliales dans des conditions de glucose élevé/hypoxique et favorise l'angiogenèse.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 60934-46-5
Sample solution is provided at 25 µL, 10mM.
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α-Tocopherol phosphate (alpha-Tocopherol phosphate) disodium, a promising antioxidant, can protect against long-wave UVA1 induced cell death and scavenge UVA1 induced ROS in a skin cell model. α-Tocopherol phosphate disodium possesses therapeutic potential in the inhibition of apoptosis and increases the migratory capacity of endothelial progenitor cells under high-glucose/hypoxic conditions and promotes angiogenesis[1][2].
[1]. Saleh MM, et al. The photoprotective properties of α-tocopherol phosphate against long-wave UVA1 (385 nm) radiation in keratinocytes in vitro. Sci Rep. 2021 Nov 17;11(1):22400.
[2]. Wu Z, et al. α-Tocopherol, especially α-tocopherol phosphate, exerts antiapoptotic and angiogenic effects on rat bone marrow-derived endothelial progenitor cells under high-glucose and hypoxia conditions. J Vasc Surg. 2018 Apr;67(4):1263-1273.e1.
| Cas No. | 60934-46-5 | SDF | |
| Synonymes | alpha-Tocopherol phosphate disodium; TocP disodium; Vitamin E phosphate disodium | ||
| Formula | C29H49Na2O5P | M.Wt | 554.65 |
| Solubility | Storage | Store at -20°C, protect from light | |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 1.8029 mL | 9.0147 mL | 18.0294 mL |
| 5 mM | 0.3606 mL | 1.8029 mL | 3.6059 mL |
| 10 mM | 0.1803 mL | 0.9015 mL | 1.8029 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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