ABBV-744 |
Catalog No.GC19409 |
ABBV-744 est un inhibiteur sélectif et actif par voie orale, premier de sa catégorie, du domaine BDII des protéines de la famille BET avec des valeurs IC50 allant de 4 À 18 nM pour BRD2, BRD3, BRD4 et BRDT.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2138861-99-9
Sample solution is provided at 25 µL, 10mM.
ABBV-744 is a BDII-selective BET bromodomain inhibitor that is being investigated to treat AML and metastic castration-resistant prostate cancer.
Reference
[1]. FIDANZE, Steven D., et al. BROMODOMAIN INHIBITORS. WO 2017177955 A1.
Average Rating: 5
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