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Akt Substrate (trifluoroacetate salt) (Synonyms: RPRAATF)

Catalog No.GC52443

An Akt peptide substrate

Products are for research use only. Not for human use. We do not sell to patients.

Akt Substrate (trifluoroacetate salt) Chemical Structure

Taille Prix Stock Qté
5 mg
70,00 $US
En stock
10 mg
126,00 $US
En stock
25 mg
277,00 $US
En stock
50 mg
486,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

Akt substrate is a peptide substrate for Akt, a serine/threonine kinase involved in various cellular processes such as proliferation, viability, angiogenesis, and glucose metabolism.1 It has been used as a target substrate for the quantification of Akt activity.

1.Bozinovski, S., Cristiano, B.E., Marmy-Conus, N., et al.The synthetic peptide RPRAATF allows specific assay of Akt activity in cell lysatesAnal. Biochem.305(1)32-39(2002)

Chemical Properties

Cas No. SDF Download SDF
Synonymes RPRAATF
Canonical SMILES OC([C@H](CC1=CC=CC=C1)NC([C@H]([C@H](O)C)NC([C@H](C)NC([C@H](C)NC([C@H](CCCNC(N)=N)NC([C@H]2N(C([C@H](CCCNC(N)=N)N)=O)CCC2)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
Formula C36H59N13O9 ? XCF3COOH M.Wt 817.9
Solubility DMF: insol,DMSO: 10 mg/ml,Ethanol: insol,PBS (pH 7.2): 5 mg/ml Storage -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 1.2226 mL 6.1132 mL 12.2264 mL
5 mM 0.2445 mL 1.2226 mL 2.4453 mL
10 mM 0.1223 mL 0.6113 mL 1.2226 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
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Review for Akt Substrate (trifluoroacetate salt)

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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