β3-AR agonist 2 |
| Catalog No.GC31573 |
β3-AR agonist 2 est un agoniste puissant et sélectif des récepteurs β3-adrénergiques (β3-AR) avec une EC50 de 8 nM.
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Cas No.: 340757-05-3
Sample solution is provided at 25 µL, 10mM.
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β3-AR agonist 2 is a potent and selective β3-adrenergic receptor (β3-AR) agonist with an EC50 of 8 nM.
β3-AR agonist 2 (Compound 26e) is found to be potent and selective at the β3 receptor, nearly completely abolishes intrinsic activity at either the β1 or β2 receptor[1].
β3-AR agonist 2 (Compound 26e) has significant thermogenesis effects on human β3-adrenergic receptor transgenic mice. β3-AR agonist 2 acts as a potential drug for the treatment of human obesity and type II diabetes[1].
[1]. Hu B, et al. (4-Piperidin-1-yl)phenyl amides: potent and selective human beta(3) agonists. J Med Chem. 2001 Apr 26;44(9):1456-66.
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