4-oxo Cyclophosphamide (Synonyms: 4-keto CP, 4-keto Cyclophosphamide, NSC 139488, 4-oxo CP) |
| Catalog No.GC49127 |
An inactive metabolite of cyclophosphamide
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Cas No.: 27046-19-1
Sample solution is provided at 25 µL, 10mM.
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4-oxo Cyclophosphamide is an inactive metabolite of the alkylating agent cyclophosphamide .1,2 It is formed from cyclophosphamide through a 4-hydroxycyclophosphamide intermediate by aldehyde dehydrogenases.2
1.Struck, R.F., Kirk, M.C., Mellett, L.B., et al.Urinary metabolites of the antitumor agent cyclophosphamideMol. Pharmacol.7(5)519-529(1971) 2.de Jonge, M.E., Huitema, A.D.R., Rodenhuis, S., et al.Clinical pharmacokinetics of cyclophosphamideClin. Pharmacokinet.44(11)1135-1164(2005)
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