12-hydroxy Stearic Acid (Synonyms: 12-HSA, NSC 2385) |
| Catalog No.GC49310 |
L'acide 12-hydroxy stéarique est un organogélateur de faible poids moléculaire structurellement simple et rentable, et ses sels et dérivés métalliques trouvent un rôle dans de nombreuses applications importantes.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 106-14-9
Sample solution is provided at 25 µL, 10mM.
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12-hydroxy Stearic acid is a hydroxy fatty acid produced by the hydrogenation of ricinoleic acid .1 It is a low molecular weight gelator that self-assembles to form organogels.2 Administration of paclitaxel in 12-hydroxy stearic acid-containing gel nanocarriers enhances tumor growth suppression in an H22 murine hepatocellular carcinoma model.3 Formulations containing 12-hydroxy stearic acid have been used in cosmetic products as emollients.
1.Fameau, A.-L., and Rogers, M.A.The curious case of 12-hydroxystearic acid — the Dr. Jekyll & Mr. Hyde of molecular gelatorsCurr. Opin. Colloid Interface Sci.4568-82(2020) 2.Burkhardt, M., Noirez, L., and Gradzielski, M.Organogels based on 12-hydroxy stearic acid as a leitmotif: Dependence of gelation properties on chemical modificationsJ. Colloid Interface Sci.466369-376(2016) 3.He, W., Lv, Y., Zhao, Y., et al.Core-shell structured gel-nanocarriers for sustained drug release and enhanced antitumor effectInt. J. Pharm.484(1-2)163-171(2015)
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