Accueil>>Signaling Pathways>> Proteases>> Endogenous Metabolite>>(-)-Cotinine

(-)-Cotinine (Synonyms: NIH 10498)

Catalog No.GC17470

La (-)-cotinine ((-)-(-)-cotinine), un alcaloïde du tabac et un métabolite majeur de la nicotine, est utilisée comme indicateur biologique pour mesurer la composition de la fumée de tabac

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(-)-Cotinine Chemical Structure

Cas No.: 486-56-6

Taille Prix Stock Qté
10mM (in 1mL DMSO)
37,00 $US
En stock
50mg
61,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

Cotinine is an alkaloid found in tobacco and is also the predominant metabolite of nicotine, used as a biomarker for exposure to tobacco smoke.

Chemical Properties

Cas No. 486-56-6 SDF
Synonymes NIH 10498
Chemical Name (S)-1-methyl-5-(pyridin-3-yl)pyrrolidin-2-one
Canonical SMILES O=C1N(C)[C@H](C2=CC=CN=C2)CC1
Formula C10H12N2O M.Wt 176.22
Solubility DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 10 mg/ml Storage Desiccate at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 5.6747 mL 28.3736 mL 56.7472 mL
5 mM 1.1349 mL 5.6747 mL 11.3494 mL
10 mM 0.5675 mL 2.8374 mL 5.6747 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Review for (-)-Cotinine

Average Rating: 5 ★★★★★ (Based on Reviews and 40 reference(s) in Google Scholar.)

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