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γ-Secretase modulator 4

Catalog No.GC38011

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γ-Secretase modulator 4 Chemical Structure

Cas No.: 1420200-82-3

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

γ-Secretase modulator 4 is a potent γ-secretase modulator, reduces the Aβ42 level with IC50s of 0.014 μM and 0.017 μM in human and mouse, respectively[1]. IC50: 0.014 μM (Aβ42, human), 0.017 μM (Aβ42, mouse)[1]

[1]. Bischoff FP, et al. Design and synthesis of a novel series of cyanoindole derivatives as potent γ-secretase modulators. Bioorg Med Chem Lett. 2019 Jul 15;29(14):1737-1745.

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