[Orn8]-Urotensin II (human) (trifluoroacetate salt) |
| Catalog No.GC45281 |
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![[Orn8]-Urotensin II (human) (trifluoroacetate salt) Chemical Structure](/media/struct/GC4/GC45281.png "[Orn8]-Urotensin II (human) (trifluoroacetate salt) Chemical Structure")
Sample solution is provided at 25 µL, 10mM.
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[Orn8]-Urotensin II is a peptide analog of urotensin II and agonist of the urotensin II receptor (UTR; EC50s = 11.74 and 8.7 nM in HEK293 cells expressing the human and rat receptor, respectively).1 It reduces urotensin II-induced contraction of isolated rat aorta (pA2 = 6.56) but has no effect on aortic contraction when used alone at concentrations up to 10 μM.
References
1. Camarda, V., Guerrini, R., Kostenis, E., et al. A new ligand for the urotensin II receptor. Br. J. Pharmacol. 137(3), 311-314 (2002).
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