L-Glutathione Reduced (Synonyms: GSH) |
Catalog No.GC12203 |
Utilisé pour éluer la GST de l'agarose de glutathion.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 70-18-8
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
- View current batch:
- Purity: >99.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Le glutathion réduit (GSH ; γ-L-glutamyl-L-cystéinyl-glycine) est un antioxydant endogène capable de neutraliser les radicaux libres dérivés de l'oxygène.
La L-glutathion réduite est un thiol non-protéique largement présent dans les cellules vivantes. La L-glutathion réduite joue des fonctions biologiques importantes dans l'organisme, notamment la synthèse de protéines et d'ADN, l'activité enzymatique, le métabolisme et la protection cellulaire. La L-glutathion réduite est capable de neutraliser les radicaux libres dérivés de l'oxygène et est établie comme marqueur du stress oxydatif[1].
References:
[1]. Pereira-Rodrigues N, et al. Electrocatalytic activity of cobalt phthalocyanine CoPc adsorbed on a graphite electrode for the oxidation of reduced L-glutathione (GSH) and the reduction of its disulfide (GSSG) at physiological pH. Bioelectrochemistry. 2007 Jan;70(1):147-54.
Cas No. | 70-18-8 | SDF | |
Synonymes | GSH | ||
Chemical Name | (S)-2-amino-5-(((R)-1-((carboxymethyl)amino)-3-mercapto-1-oxopropan-2-yl)amino)-5-oxopentanoic acid | ||
Canonical SMILES | SC[C@@H](C(NCC(O)=O)=O)NC(CC[C@@H](C(O)=O)N)=O | ||
Formula | C10H17N3O6S | M.Wt | 307.32 |
Solubility | ≥ 14.25mg/mL in Water | Storage | 4°C, protect from light ,unstable in solution, ready to use. |
General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. |
Prepare stock solution | |||
1 mg | 5 mg | 10 mg | |
1 mM | 3.2539 mL | 16.2697 mL | 32.5394 mL |
5 mM | 0.6508 mL | 3.2539 mL | 6.5079 mL |
10 mM | 0.3254 mL | 1.627 mL | 3.2539 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Average Rating: 5
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