Sphingolipids
Products for Sphingolipids
- Cat.No. Nom du produit Informations
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GC45206
α-GalCer analog 8
α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide.
- GC45263 (+)-D-threo-PDMP (hydrochloride) (+)-D-threo-PDMP is a ceramide analog and is one of the four possible stereoisomers of PDMP.
- GC45250 (-)-L-threo-PDMP (hydrochloride) (-)-L-threo-PDMP is an enhancer of ganglioside biosynthesis.
- GC41268 (E)-2-Hexadecenal Sphingosine-1-phosphate (S1P), a bioactive lipid involved in many signaling processes, is irreversibly degraded by the membrane-bound S1P lyase.
- GC41701 (E)-2-Hexadecenal Alkyne (E)-2-Hexadecenal alkyne is an alkyne version of the sphingolipid degradation product (E)-2-hexadecenal that can be used as a click chemistry probe.
- GC42050 1-β-D-Glucosylsphingadienine (d18:2 (4E,8E)) 1-β-D-Glucosylsphingadiénine (d18:2 (4E,8E)) est une glucosylsphingosine, qui sont des dérivés lysolipidiques désacétylés de glucosylcérébrosides.
- GC42051 1-β-D-Glucosylsphingosine (d18:1) 1-β-D-Glucosylsphingosine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucocerebrosides.
- GC18609 1-Deoxysphinganine (m18:0) La 1-désoxysphinganine (m18:0) (ES-285) est un composé antiprolifératif (antitumoral) d'origine marine. La 1-désoxysphinganine (m18:0) inhibe la croissance des cellules prostatiques PC-3 et LNCaP par accumulation intracellulaire de céramide et PKC&zeta ; Activation.
- GC41544 1-Deoxysphingosine (m18:1(14Z)) 1-Deoxysphingosine (m18:1(14Z)) is an atypical sphingolipid that contains a double bond at the n-4 (14Z) native position and is formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.
- GC46050 1-Deoxysphingosine (m18:1(4E)) An atypical sphingolipid
- GC41907 13C C16 Sphingomyelin (d18:1/16:0) 13C C16 Sphingomyelin is an isotopically enriched form of C16 sphingomyelin with carbon-13 occurring on the fatty acid portion.
- GC41908 13C6 Glucosylsphingosine (d18:1) 13C6 Glucosylsphingosine (d18:1) is an isotopically enriched form of 1-β-D-glucosylsphingosine (d18:1) that is intended for use as an internal standard for the quantification of 1-β-D-glucosylsphingosine by GC- or LC-MS.
- GC42112 2-Acetyl-5-tetrahydroxybutyl Imidazole Sphingosine-1-phosphate (S1P) lyase catalyzes the irreversible decomposition of S1P to hexadecanaldehyde and phosphoethanolamine.
- GC42242 3'-sulfo Galactosylsphingosine (ammonium salt) 3'-sulfo Galactosylsphingosine is a form of sulfatide that is lacking the fatty acyl group.
- GC42295 3-keto Sphinganine (d12:0) (hydrochloride) 3-keto Sphinganine (d12:0) is a short-chain analog of the typical C18 chain-length 3-keto sphinganine (d18:0).
- GC42297 3-keto Sphinganine (d6:0) (hydrochloride) 3-keto Sphinganine (d6:0) is a short-chain analog of the typical C18 chain-length 3-keto sphinganine (d18:0).
- GC42298 3-keto Sphinganine (d8:0) (hydrochloride) 3-keto Sphinganine (d8:0) is a short-chain analog of the typical C18 chain-length 3-keto sphinganine (d18:0).
- GC42369 4-Deoxypyridoxine (hydrochloride) 4-Deoxypyridoxine (4-DPD) is a vitamin B6 antimetabolite with diverse biological activities.
- GC46765 A6770 A6770 est un puissant inhibiteur de la sphingosine 1-phosphate (S1P) lyase (S1PL) actif par voie orale.
- GC41406 AMP-Deoxynojirimycin The lipid messenger ceramide is converted to glucosylceramide by glucosylceramide synthase (GCS).
- GC42854 ARN14988 ARN14988 est un puissant inhibiteur de la céramidase acide (ACDase) (IC50 = 12,8 nM pour l'enzyme humaine).
- GC42891 azido-FTY720 Azido-FTY720 est un analogue photoactivable du FTY720.
- GC42963 BODIPY-C12 Ceramide (d18:1/12:0) BODIPY-C12 Ceramide (B12Cer) is a fluorescently-tagged form of C12 ceramide that displays excitation/emission maxima of 505/540 nm, respectively.
- GC43003 C10 AV Ceramide (d18:1/10:0) AV-Ceramide is a fluorescently-tagged probe consisting of C-10 ceramide with an anthrylvinyl (AV) group attached to the end of the acyl chain.
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GC43004
C10 Ceramide (d18:1/10:0)
C10 ceramide is an endogenous, bioactive sphingolipid produced by ceramide synthase.
- GC46974 C12 1-Deoxyceramide (m18:1/12:0) A medium-chain atypical ceramide
- GC43005 C12 3'-sulfo Galactosylceramide (d18:1/12:0) C12 3'-sulfo Galactosylceramide is a sulfated glycolipid, which are also known as sulfatides.
- GC43006 C12 Ceramide (d18:1/12:0) Le céramide C12 (d18:1/12:0) (N-Lauroyl-D-érythro-sphingosine), un céramide naturel, est formé par hydrolyse de la sphingomyéline C12.
- GC43007 C12 Galactosylceramide (d18:1/12:0) C12 Galactosylceramide is a bioactive sphingolipid.
- GC43009 C12 NBD 3'-sulfo Galactosylceramide (d18:1/12:0) C12 NBD 3'-sulfo galactosylceramide is a sphingolipid that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group.
- GC43010 C12 NBD Ceramide (d18:1/12:0) C12 NBD Ceramide (d18:1/12:0) est un analogue fluorescent du céramide, il peut être utilisé comme substrat dans les dosages de céramidase.
- GC43011 C12 NBD dihydro Ceramide (d18:0/12:0) C12 NBD dihydro Ceramide (d18:0/12:0) est un substrat de céramidase fluorescent.
- GC43012 C12 NBD Galactosylceramide (d18:1/6:0) Le galactosylcéramide C12 NBD, colorant fluorescent, est un dérivé biologiquement actif du galactosylcéramide qui est étiqueté avec un groupe fluorescent C12 nitrobenzoxadiazole (C12 NBD).
- GC43013 C12 NBD Globotriaosylceramide (C18:1/12:0) C12 NBD globotriaosylceramide is a biologically active derivative of globotriaosylceramide that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD).
- GC43016 C12 NBD L-threo dihydro Ceramide (d18:0/12:0) C12 NBD L-thréo dihydro céramide (d18:0/12:0) est un groupe fluorescent.
- GC43014 C12 NBD Lactosylceramide (d18:1/12:0) Le lactosylcéramide C12 NBD (d18:1/12:0) est un dérivé du lactosylcéramide marqué avec un groupe fluorescent C12 NBD.
- GC43017 C12 NBD Phytoceramide (t18:0/12:0) C12 NBD phytoceramide is a biologically active derivative of phytosphingosine that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group.
- GC43018 C12 NBD Sphingomyelin (d18:1/12:0) C12 NBD sphingomyelin is a biologically active derivative of sphingomyelin that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group.
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GC43022
C14 Ceramide (d18:1/14:0)
C14 Ceramide is an endogenous ceramide generated by ceramide synthase 6.
- GC43023 C15 Ceramide (d18:1/15:0) C15 Ceramide is a naturally occurring ceramide that has been found in L.
- GC43024 C15 Galactosylceramide (d18:1/15:0) C15 Galactosylceramide is a glycosphingolipid.
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GC43025
C16 (2'(S)-hydroxy) Ceramide (d18:1/16:0)
C16 (2'(S)-hydroxy) Ceramide is the synthetic ceramide stereoisomer of N-(2'-(R)-hydroxypalmitoyl)-D-erythro-sphingosine.
- GC46975 C16 1-Deoxyceramide (m18:1/16:0) A long-chain atypical ceramide
- GC43026 C16 3'-sulfo Galactosylceramide (d18:1/16:0) C16 3'-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids.
- GC43027 C16 Ceramide (d16:1/16:0) C16 Ceramide (d16:1/16:0) is a bioactive sphingolipid that induces ordered- and gel-phase formation and thermal stabilization of palmitoylsphingomyelin-rich domains in palmitoylphosphocholine (POPC) bilayers.
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GC43028
C16 Ceramide (d18:1/16:0)
Les céramides sont générés à partir de la sphingomyéline par activation des sphingomyélinases ou par la voie de synthèse de novo, qui nécessite une action coordonnée de la sérine palmitoyl transférase et de la ceramide synthase.
- GC43029 C16 Ceramide-1-phosphate (d18:1/16:0) (ammonium salt) C16 Ceramide-1-phosphate (C16 C1P) is one of the main forms of C1P found in cells.
- GC46976 C16 Ceramide-d7 (d18:1-d7/16:0) An internal standard for the quantification of C-16 ceramide
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GC43030
C16 dihydro Ceramide (d18:0/16:0)
A bioactive sphingolipid
- GC43031 C16 Galactosylceramide (d18:1/16:0) C16 Galactosylceramide is a glycosphingolipid that contains a galactose moiety attached to a ceramide acylated with palmitic acid .
- GC43032 C16 Globotriaosylceramide (d18:1/16:0) C16 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from C16 lactosylceramide.
- GC43033 C16 Lactosylceramide (d18:1/16:0) C16 Lactosylceramide is an endogenous bioactive sphingolipid.
- GC43034 C16 Phytoceramide (t18:0/16:0) C16 Phytoceramide (t18:0/16:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis.
- GC43035 C16 Sphingomyelin (d18:1/16:0) Sphingomyelins are complex membrane lipids composed of phosphorylcholine, sphingosine, and an acylated group, such as a fatty acid.
- GC43036 C16((±)-2'-hydroxy) dihydro Ceramide (d18:0/16:0) C16((±)-2'-hydroxy) dihydro Ceramide (d18:0/16:0) is a 2'-hydroxylated form of C16 dihydro ceramide .
- GC43037 C17 3'-sulfo Galactosylceramide (d18:1/17:0) C17 3'-sulfo Galactosylceramide is a synthetic sulfated glycolipid, which are also known as sulfatides.
- GC43038 C17 Ceramide (d18:1/17:0) C17 Ceramide is a synthetic ceramide that contains a non-natural C17:0 fatty acid acylated to sphingosine.
- GC43040 C17 dihydro Ceramide (d18:0/17:0) C17 dihydro Ceramide is a synthetic ceramide that contains a non-natural C17:0 fatty acid acylated to sphingosine.
- GC43041 C17 Globotriaosylceramide (d18:1/17:0) C17 Globotriaosylceramide is a sphingolipid that has been used as an internal standard for the quantification of globotriaosylceramides in plasma and urine from patients with Fabry disease by GC-MS.
- GC43042 C17 Lactosylceramide (d18:1/17:0) C17 Lactosylceramide is a naturally occurring sphingolipid that has been found in human brain metastases of lung adenocarcinomas but not in healthy brain tissue.
- GC43043 C17 Sphingomyelin (d18:1/17:0) C17 Sphingomyelin is a synthetic derivative of sphingomyelin that has been used as an internal standard for the quantification of sphingomyelin.
- GC43044 C18 ((±)-2'-hydroxy) Ceramide (d18:1/18:0) C18 ((±)-2'-hydroxy) Ceramide (d18:1/18:0) (18:0 (2R/S-OH)-Ceramide) is a bioactive sphingolipid found in the stratum corneum layer of mammalian epidermis.
- GC43045 C18 ((±)-2'-hydroxy) dihydro Ceramide (d18:0/18:0) C18 ((±)-2'-hydroxy) dihydro Ceramide (d18:0/18:0) is a 2'-hydroxylated form of C18 dihydro ceramide .
- GC43046 C18 3'-sulfo Galactosylceramide (d18:1/18:0) C18 3'-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids.
- GC40140 C18 3'-sulfo Lactosylceramide (d18:1/18:0) C18 3'-sulfo Lactosylceramide (d18:1/18:0) is a sulfated glycosphingolipid.
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GC43047
C18 Ceramide (d18:1/18:0)
C18 Ceramide is an endogenous bioactive sphingolipid.
- GC46987 C18 Ceramide-d3 (d18:1/18:0-d3) An internal standard for the quantification of C18 ceramide
- GC46988 C18 Ceramide-d7 (d18:1-d7/18:0) An internal standard for the quantification of C18 ceramide
- GC48425 C18 D-threo Ceramide (d18:1/18:0) A synthetic ceramide
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GC43048
C18 dihydro Ceramide (d18:0/18:0)
A bioactive sphingolipid
- GC46990 C18 Galactosylceramide-d35 (d18:1/18:0-d35) An internal standard for the quantification of C18 galactosylceramide
- GC49806 C18 Ganglioside GD3-d3 (ammonium salt) An internal standard for the quantification of ganglioside GD3
- GC43049 C18 Globotriaosylceramide (d18:1/18:0) C18 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from lactosylceramide.
- GC43050 C18 L-erythro Ceramide (d18:1/18:0) C18 L-erythro Ceramide is a naturally occurring ceramide and stereoisomer of C18 ceramide.
- GC43051 C18 L-threo Ceramide (d18:1/18:0) C18 L-threo Ceramide is a synthetic ceramide and stereoisomer of C18 ceramide that has been used for structural characterization of natural sphingolipids.
- GC43052 C18 Phytoceramide (t18:0/18:0) C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid found in S.
- GC40141 C18 Phytoceramide-d3 (t18:0/18:0-d3) C18 Phytoceramide-d3 (t18:0/18:0-d3) is intended for use as an internal standard for the quantification of C18 phytoceramide (t18:0/18:0) by GC- or LC-MS.
- GC43053 C18 Sphingomyelin (d18:1/18:0) C18 Sphingomyelin is a naturally occurring form of sphingomyelin.
- GC43054 C18:1 3'-sulfo Galactosylceramide (d18:1/18:1(9Z)) C18:1 3'-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids.
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GC43055
C18:1 Ceramide (d18:1/18:1(9Z))
C18:1 Ceramide is a naturally occurring ceramide.
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GC43057
C19 Ceramide (d18:1/19:0)
C19 Ceramide is a naturally occurring ceramide that has been found in J.
- GC43058 C2 3'-sulfo Galactosylceramide (d18:1/2:0) C2 3'-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids.
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GC43059
C2 Adamantanyl Galactosylceramide (d18:1/2:0)
C2 Adamantanyl Galactosylceramide (d18:1/2:0) (AdaGalCer) is a bioactive sphingolipid.
- GC43060 C2 Adamantanyl Globotriaosylceramide (d18:1/2:0) C2 Adamantanyl globotriaosylceramide (AdaGb3) is a bioactive sphingolipid and water-soluble form of globotriaosylceramide that contains an adamantanyl group in place of the fatty acyl chain.
- GC43061 C2 Adamantanyl Glucosylceramide (d18:1/2:0) C2 Adamantanyl glucosylceramide (AdaGluCer) is a bioactive sphingolipid.
- GC43062 C2 Ceramide (d14:1/2:0) C2 Ceramide (d14:1/2:0) est une composition pour le diagnostic de maladies associées À la surexpression de la cyclooxygénase 2 (COX2). C2 Ceramide (d14:1/2:0) présente une forte activité de liaison À la protéine COX2 (extrait du brevet WO2019235824A1).
- GC43063 C2 dihydro Ceramide (d18:0/2:0) C2 dihydro Ceramide is a metabolically inactive analog of C-2 ceramide.
- GC40708 C2 L-erythro Ceramide (d18:1/2:0) C2 L-erythro Ceramide is a bioactive sphingolipid and a cell-permeable analog of naturally occurring ceramides.
- GC40709 C2 L-threo Ceramide (d18:1/2:0) C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.
- GC43065 C2 Phytoceramide (t18:0/2:0) C2 Phytoceramide is a bioactive semisynthetic sphingolipid that inhibits formyl peptide-induced oxidant release (IC50 = 0.38 μM) in suspended polymorphonuclear cells.
- GC43066 C2 Sphingomyelin (d18:1/2:0) C2 Sphingomyelin is a synthetic cell-permeable derivative of sphingomyelin.
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GC43067
C20 Ceramide (d18:1/20:0)
Ceramides are generated from sphingomyelin through activation of sphingomyelinases or through the de novo synthesis pathway.
- GC43068 C20 Sphingomyelin (d18:1/20:0) C20 Sphingomyelin is a naturally occurring sphingolipid.
- GC45663 C22 1-Deoxyceramide (m18:1(14Z)/22:0) A long-chain atypical ceramide
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GC43069
C22 Ceramide (d18:1/22:0)
C-22 ceramide is an endogenous bioactive sphingolipid.
- GC46108 C22 dihydro 1-Deoxyceramide (m18:0/22:0) A very long-chain atypical ceramide
- GC46997 C22 Galactosylceramide (d18:1/22:0) A sphingolipid
- GC43070 C22 Glucosylceramide (d18:1/22:0) C22 Glucosylceramide (d18:1/22:0) is an endogenous glucosylceramide.
- GC47000 C22 Phytoceramide (t18:0/22:0) A sphingolipid
- GC47001 C22 Phytoceramide-d3 (t18:0/22:0-d3) An internal standard for the quantification of C22 phytoceramide