Phenacetin-d5 (Synonyms: Acetophenetidin-d5) |
| Catalog No.GC66429 |
La phénacétine-d5 (acétophénétidine-d5) est la phénacétine marquée au deutérium. La phénacétine (acétophénétidine) est un analgésique/antipyrétique non opioÏde. La phénacétine est un inhibiteur sélectif de la COX-3. La phénacétine est utilisée comme sonde des enzymes du cytochrome P450 CYP1A2 dans les microsomes hépatiques humains et chez le rat.
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Cas No.: 69323-74-6
Sample solution is provided at 25 µL, 10mM.
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Phenacetin-d5 (Acetophenetidin-d5) is the deuterium labeled Phenacetin. Phenacetin (Acetophenetidin) is a non-opioid analgesic/antipyretic agent. Phenacetin is a selective COX-3 inhibitor. Phenacetin is used as probe of cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats[1][2][3].
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
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