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(R)-ZINC 3573

Catalog No.GC50426

MRGPRX2 agonist

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(R)-ZINC 3573 Chemical Structure

Cas No.: 2089389-15-9

Taille Prix Stock Qté
5 mg
113,00 $US
En stock
25 mg
446,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Mas-related G protein-coupled receptor X2 (MRGPRX2) agonist (EC50 = 0.74 μM). Displays selectivity for MRGPRX2 over 350 other GPCRs, including MRGPRX1. Induces intracellular calcium release and degranulation in LAD2 mast cells in vitro. Negative control (S)-ZINC 3573 also available.

Lansu et al (2017) In silico design of novel probes for the atypical opioid receptor MRGPRX2. Nat.Chem.Biol. 13 529 PMID:28288109

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Average Rating: 5 ★★★★★ (Based on Reviews and 9 reference(s) in Google Scholar.)

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