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(Rac)-MEM 1003

Catalog No.GC61873

(Rac)-MEM 1003 est le racémate du MEM 1003.

Products are for research use only. Not for human use. We do not sell to patients.

(Rac)-MEM 1003 Chemical Structure

Cas No.: 165187-25-7

Taille Prix Stock Qté
10mM (in 1mL DMSO)
297,00 $US
En stock
5 mg
270,00 $US
En stock
10 mg
432,00 $US
En stock
25 mg
855,00 $US
En stock
50 mg
1 305,00 $US
En stock
100 mg
2 025,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

(Rac)-MEM 1003 is the racemate of MEM 1003. MEM 1003, a dihydropyridine compound, is a potent L-type Ca2+ channel antagonist and has the potential for Alzheimer's disease research[1].

References:
[1]. Gregory M Rose, et al. Efficacy of MEM 1003, a novel calcium channel blocker, in delay and trace eyeblink conditioning in older rabbits. Neurobiol Aging. 2007 May;28(5):766-73.

Chemical Properties

Cas No. 165187-25-7 SDF
Canonical SMILES O=C(OCCOC)C1=C(NC(C)=C(C1C2=CC=CC(C#N)=C2Cl)C(OC(C)C)=O)C
Formula C22H25ClN2O5 M.Wt 432.9
Solubility DMSO : 125 mg/mL (288.75 mM; ultrasonic and warming and heat to 80°C) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.31 mL 11.55 mL 23.1 mL
5 mM 0.462 mL 2.31 mL 4.62 mL
10 mM 0.231 mL 1.155 mL 2.31 mL
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In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Review for (Rac)-MEM 1003

Average Rating: 5 ★★★★★ (Based on Reviews and 1 reference(s) in Google Scholar.)

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