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Accueil >> Signaling Pathways >> Apoptosis >> Pyroptosis

Pyroptosis

Products for  Pyroptosis

  1. Cat.No. Nom du produit Informations
  2. GA20494 Ac-Asp-Glu-Val-Asp-pNA

    Ac-Asp-Glu-Val-Asp-pNA

     The cleavage of the chromogenic caspase-3 substrate Ac-DEVD-pNA can be monitored at 405 nm. Ac-Asp-Glu-Val-Asp-pNA Chemical Structure
  3. GC48470 Ac-DEVD-CHO (trifluoroacetate salt)

    N-Ac-Asp-Glu-Val-Asp-CHO

     A dual caspase3/caspase7 inhibitor Ac-DEVD-CHO (trifluoroacetate salt) Chemical Structure
  4. GC65107 Ac-FEID-CMK TFA Ac-FEID-CMK TFA est un puissant inhibiteur peptidique dérivé de GSDMEb spécifique au poisson zèbre. Ac-FEID-CMK TFA Chemical Structure
  5. GC60558 Ac-FLTD-CMK Ac-FLTD-CMK, un inhibiteur dérivé de la gasdermine D (GSDMD), est un inhibiteur spécifique des caspases inflammatoires. Ac-FLTD-CMK Chemical Structure
  6. GC49704 Ac-FLTD-CMK (trifluoroacetate salt)

    Ac-Phe-Leu-Thr-Asp-CMK

     An inhibitor of caspase-1, -4, -5, and -11 Ac-FLTD-CMK (trifluoroacetate salt) Chemical Structure
  7. GC42708 Ac-LEHD-AFC (trifluoroacetate salt)

    N-Acetyl-Leu-Glu-His-Asp-7-amino-4-Trifluoromethylcoumarin, Caspase-9 substrate (Fluorogenic)

     Ac-LEHD-AFC is a fluorogenic substrate that can be cleaved by caspase-4, -5, and -9. Ac-LEHD-AFC (trifluoroacetate salt) Chemical Structure
  8. GC42709 Ac-LEVD-CHO (trifluoroacetate salt)

    Ac-Leu-Glu-Val-Asp-CHO, Caspase-4 Inhibitor I

    Ac-LEVD-CHO is a caspase-4 inhibitor.

     Ac-LEVD-CHO (trifluoroacetate salt) Chemical Structure
  9. GC40124 Ac-WEAD-AMC (trifluoroacetate salt)

    Ac-Trp-Glu-Ala-Asp-AMC

     Ac-WEAD-AMC is a fluorogenic substrate for caspase-1 and caspase-4. Ac-WEAD-AMC (trifluoroacetate salt) Chemical Structure
  10. GC42719 Ac-WEAD-pNA (trifluoroacetate salt)

    Ac-Trp-Glu-Ala-Asp-pNA, Ac-Trp-Glu-Ala-Asp-p-nitroanilide, Caspase-1 and Caspase-4 Chromogenic Substrate

     Ac-WEAD-pNA is a colorimetric substrate for caspase-1 and caspase-4. Ac-WEAD-pNA (trifluoroacetate salt) Chemical Structure
  11. GC46796 Ac-WEHD-AFC (trifluoroacetate salt)

    N-Acetyl-Trp-Glu-His-Asp-7-amino-4-Trifluoromethylcoumarin, Caspase1 Substrate (Fluorogenic), Caspase5 Substrate (Fluorogenic)

     A neuropeptide with diverse biological activities Ac-WEHD-AFC (trifluoroacetate salt) Chemical Structure
  12. GC18021 Ac-YVAD-CHO

    Caspase-1 Inhibitor I, L 709049, N-Ac-Tyr-Val-Ala-Asp-CHO

     Ac-YVAD-CHO (L-709049) est un inhibiteur puissant, réversible et spécifique de l'enzyme de conversion de l'interleukine-lβ tétrapeptidique (ICE) avec des valeurs de Ki chez la souris et l'homme de 3,0 et 0,76 nM. Ac-YVAD-CHO Chemical Structure
  13. GC42721 Ac-YVAD-CMK

    N-Ac-Tyr-Val-Ala-Asp-CMK

     Ac-YVAD-CMK est un inhibiteur irréversible sélectif de la caspase-1 (Ki=0,8nM), capable de prévenir l'activation de la cytokine pro-inflammatoire IL-1β. Ac-YVAD-CMK peut réduire la réponse inflammatoire et induire un effet neuroprotecteur durable. Ac-YVAD-CMK Chemical Structure
  14. GC40149 Boc-AEVD-CHO (trifluoroacetate salt)

    Boc-Ala-Glu-Val-Asp-CHO

     Boc-AEVD-CHO is an inhibitor of caspase-8 (Ki = 1.6 nM) that also inhibits caspase-1, -3, -6, and -9 (Kis = 10,000, 375, 438, 425, and 320 nM, respectively). Boc-AEVD-CHO (trifluoroacetate salt) Chemical Structure
  15. GC18421 Dabcyl-YVADAPV-EDANS

    Dabcyl-ICE-EDANS

     Dabcyl-YVADAPV-EDANS is a fluorogenic substrate for caspase-1. Dabcyl-YVADAPV-EDANS Chemical Structure
  16. GC91060 Ferritin PROTAC DeFer-2

    Un PROTAC qui induit la dégradation de la ferritine.

     Ferritin PROTAC DeFer-2 Chemical Structure
  17. GC43668 FITC-C6-YVADAP-K(Dnp) (trifluoroacetate salt)

    FITC-C6-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH

     FITC-C6-YVADAP-K(Dnp) is a caspase-1 fluorogenic substrate. FITC-C6-YVADAP-K(Dnp) (trifluoroacetate salt) Chemical Structure
  18. GC74070 INF 195 INF 195 est un inhibiteur de NLRP3. INF 195 Chemical Structure
  19. GC65393 LDC7559 Le LDC7559 est un inhibiteur de la gasdermine D (GSDMD) via le blocage du piège extracellulaire des neutrophiles (NET) aux stades avancés . LDC7559 Chemical Structure
  20. GC40120 Mca-LEVDGW-K(Dnp)-NH2 (trifluoroacetate salt)

    Mca-Leu-Glu-Val-Asp-Gly-Trp-Lys(Dnp)-NH2

     Mca-LEVDGW-K(Dnp)-NH2 is a fluorogenic substrate for caspase-4. Mca-LEVDGW-K(Dnp)-NH2 (trifluoroacetate salt) Chemical Structure
  21. GC47607 Mca-YVADAP-K(Dnp)-OH (trifluoroacetate salt)

    Caspase-1 Fluorogenic Substrate V, Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(DNP)-OH, Mca-YVADAP-Lys(Dnp)-OH, (7-Methoxycoumarin-4-yl)acetyl-YVADAPK(2,4-dinitrophenyl)-OH

     A neuropeptide with diverse biological activities Mca-YVADAP-K(Dnp)-OH (trifluoroacetate salt) Chemical Structure
  22. GC49681 Necrosulfonamide-d4

    NSA-d4

     Le nécrosulfonamide-d4 est le nécrosulfonamide marqué au deutérium. Le nécrosulfonamide est un inhibiteur de la nécroptose agissant en ciblant sélectivement la protéine de type domaine kinase de lignée mixte (MLKL). Le nécrosulfonamide empêche le complexe nécrosome MLKL-RIP1-RIP3 d'interagir avec ses effecteurs en aval. MLKL est un substrat critique de RIP3 lors de l'induction de la nécrose. Necrosulfonamide-d4 Chemical Structure
  23. GC49024 Palmitic Acid MaxSpec® Standard

    C16:0, Cetylic Acid, NSC 5030

     A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Palmitic Acid MaxSpec® Standard Chemical Structure
  24. GC49023 Palmitic Acid-d9 MaxSpec® Standard

    C16:0-d9, Cetylic Acid-d9

     A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Palmitic Acid-d9 MaxSpec® Standard Chemical Structure
  25. GC72191 Pep19-2.5 Pep19-2.5 est un peptide synthétique et antitoxine, bloque la cascade de signalisation endotoxine intracellulaire. Pep19-2.5 Chemical Structure
  26. GC44967 Suc-YVAD-AMC (acetate)

    Suc-Tyr-Val-Ala-Asp-AMC, Suc-Tyr-Val-Ala-Asp-7-amino-4-methylcoumarin, Suc-YVAD-NH-Mec

     Suc-YVAD-AMC is a fluorogenic substrate for caspase-1. Suc-YVAD-AMC (acetate) Chemical Structure
  27. GC45175 YVAD-CHO (trifluoroacetate salt)

    H-Tyr-Val-Ala-Asp-CHO

     YVAD-CHO is an inhibitor of caspase-1/interleukin-1β converting enzyme (ICE) and a non-acetylated form of Ac-YVAD-CHO. YVAD-CHO (trifluoroacetate salt) Chemical Structure
  28. GC45178 Z-DEVD-CMK (trifluoroacetate salt)

    Z-Asp-Glu-Val-Asp-CMK

    Z-DEVD-CMK is a protease inhibitor.

     Z-DEVD-CMK (trifluoroacetate salt) Chemical Structure
  29. GC40151 Z-VAD-AMC (acetate)

    Z-Val-Ala-Asp-AMC, Z-Val-Ala-Asp-7-amino-4-methylcoumarin

     Z-VAD-AMC is a fluorogenic substrate for caspase-1. Z-VAD-AMC (acetate) Chemical Structure
  30. GC40153 Z-YVAD-AFC (trifluoroacetate salt)

    Z-Tyr-Val-Ala-Asp-AFC, Z-Tyr-Val-Ala-Asp-7-amino-4-trifluoromethylcoumarin, Z-YVAD-7-amino-4-trifluoromethylcoumarin

     Z-YVAD-AFC is a fluorogenic substrate for caspase-1. Z-YVAD-AFC (trifluoroacetate salt) Chemical Structure
  31. GC45193 Z-YVAD-CMK (trifluoroacetate salt)

    Benxyloxycarbonyl-Tyr-Val-Ala-Asp-Chloromethylketone, Caspase-1 Inhibitor IV

    Z-YVAD-CMK is an inhibitor of caspase-1 and caspase-3.

     Z-YVAD-CMK (trifluoroacetate salt) Chemical Structure
  32. GC40119 Z-YVADLD-FMK (trifluoroacetate salt)

    Z-Tyr-Val-Ala-Asp-Leu-Asp-FMK

     Z-YVADLD-FMK is a peptide that contains the amino acid sequence YVAD, which is the cleavage site for caspase-1 and -4. Z-YVADLD-FMK (trifluoroacetate salt) Chemical Structure

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