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Accueil >> Signaling Pathways >> Immunology/Inflammation >> Autoimmunity

Autoimmunity

Products for  Autoimmunity

  1. Cat.No. Nom du produit Informations
  2. GC52253 α-Enolase (1-19)-biotin Peptide

    Enolase-1 (1-19)-biotin

     A biotinylated α-enolase peptide α-Enolase (1-19)-biotin Peptide Chemical Structure
  3. GC48292 α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

    α-Melanocyte-stimulating Hormone, Ac-SYSMEHFRWGKPV-NH2

     α-MSH (α-Melanocyte-Stimulating Hormone) TFA, un neuropeptide endogène, est un agoniste endogène du récepteur 4 de la mélanocortine (MC4R) avec des activités anti-inflammatoires et antipyrétiques. α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) Chemical Structure
  4. GC40467 (±)11-HETE

    (±)11-Hydroxyeicosatetraenoic Acid

     (±)11-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. (±)11-HETE Chemical Structure
  5. GC45263 (+)-D-threo-PDMP (hydrochloride)

    D-PDMP

     (+)-D-threo-PDMP is a ceramide analog and is one of the four possible stereoisomers of PDMP. (+)-D-threo-PDMP (hydrochloride) Chemical Structure
  6. GC52185 (R,S)-Anatabine-d4

    (±)-Anatabine-d4

     (R,S)-Anatabine-d4 Chemical Structure
  7. GC18773 (Rac)-Benpyrine La (Rac)-benpyrine, un racémate de la benpyrine, est un puissant inhibiteur du TNF-α actif par voie orale. (Rac)-Benpyrine Chemical Structure
  8. GC90774 1-Linoleoyl Lysophosphatidic Acid (sodium salt)

    Un glycérophospholipide

     1-Linoleoyl Lysophosphatidic Acid (sodium salt) Chemical Structure
  9. GC46499 1-Stearoyl-rac-glycerol-d40

    18:0-d40-MG, 1-Monostearin-d40, MG(18:0-d40/0:0/0:0)

     A neuropeptide with diverse biological activities 1-Stearoyl-rac-glycerol-d40 Chemical Structure
  10. GC49759 13C17-Mycophenolic Acid

    13C17-MPA

     An internal standard for the quantification of mycophenolic acid 13C17-Mycophenolic Acid Chemical Structure
  11. GC49912 13C20,15N10-Cyclic di-GMP (sodium salt)

    13C20,15N10-c-di-GMP, 13C20,15N10-Cyclic diguanylate, 13C20,15N10-3’,5’-Cyclic diguanylic Acid

     An internal standard for the quantification of cyclic di-GMP 13C20,15N10-Cyclic di-GMP (sodium salt) Chemical Structure
  12. GC41950 16α-hydroxy Estrone

    16α-hydroxy E1, 16αOHE1

     16α-hydroxyestrone (16αOHE) est un métabolite majeur de l'estradiol. 16α-hydroxy Estrone Chemical Structure
  13. GC42080 2'2'-cGAMP (sodium salt)

    Adenosine-Guanosine 2’,2’-cyclic monophosphate, cGAMP(2’-5’), 2’,2’-Cyclic GMP-AMP

     2'2'-cGAMP is a synthetic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds. 2'2'-cGAMP (sodium salt) Chemical Structure
  14. GC40960 20α-dihydro Prednisolone

    20α-DHP, 20α-dihydro-PRED, 20(R)-hydroxy Prednisolone, 20α-hydroxy Prednisolone

     20α-dihydro Prednisolone is a metabolite of prednisolone. 20α-dihydro Prednisolone Chemical Structure
  15. GC18527 4'-hydroxy Flurbiprofen A major active metabolite of flurbiprofen 4'-hydroxy Flurbiprofen Chemical Structure
  16. GC49127 4-oxo Cyclophosphamide

    4-keto CP, 4-keto Cyclophosphamide, NSC 139488, 4-oxo CP

     An inactive metabolite of cyclophosphamide 4-oxo Cyclophosphamide Chemical Structure
  17. GC18582 5'-hydroxy Meloxicam A metabolite of meloxicam 5'-hydroxy Meloxicam Chemical Structure
  18. GC48381 5'-pApA (sodium salt)

    c-di-AMP Control, Cyclic di-AMP Negative Control

     A linearized form of cyclic di-AMP 5'-pApA (sodium salt) Chemical Structure
  19. GC48375 5'-pGpG (sodium salt)

    c-di-GMP Control, Cyclic di-GMP Negative Control

     A linearized form of cyclic di-GMP 5'-pGpG (sodium salt) Chemical Structure
  20. GC52413 5-Aminosalicylic Acid-d7

    5-ASA-d7, Mesalamine-d7, Mesalazine-d7

     An internal standard for the quantification of 5-aminosalicylic acid 5-Aminosalicylic Acid-d7 Chemical Structure
  21. GC49629 6β-hydroxy Prednisolone A metabolite of prednisolone 6β-hydroxy Prednisolone Chemical Structure
  22. GC45772 6(5H)-Phenanthridinone

    NSC 11021, NSC 40943, NSC 61083

     An inhibitor of PARP1 and 2 6(5H)-Phenanthridinone Chemical Structure
  23. GC49235 6-Methylmercaptopurine

    6-MMP, 6-(Methylthio)purine, NSC 20105, SQ 8,343

     A metabolite of 6-mercaptopurine 6-Methylmercaptopurine Chemical Structure
  24. GC49488 6-Methylmercaptopurine-d3

    6-MMP-d3, 6-(Methylthio)purine-d3

     An internal standard for the quantification of 6-MMP 6-Methylmercaptopurine-d3 Chemical Structure
  25. GC49051 7-hydroxy Methotrexate

    NSC 380962, 7-hydroxy MTX

     Le 7-hydroxy méthotrexate est un métabolite majeur du méthotrexate 7-hydroxy Methotrexate Chemical Structure
  26. GC42608 7-hydroxy Methotrexate (sodium salt)

    7-hydroxy MTX

    7-hydroxy Methotrexate (7-hydroxy MTX) is a phase I metabolite of MTX, which is converted by hepatic aldehyde oxidases.

     7-hydroxy Methotrexate (sodium salt) Chemical Structure
  27. GC42644 9-Deazaguanine

    NSC 344522

     9-Deazaguanine is an analog of guanine that acts as an inhibitor of purine nucleoside phosphorylase (PNP; Kd = 160 nM). 9-Deazaguanine Chemical Structure
  28. GC49238 93-O17S A cationic lipidoid 93-O17S Chemical Structure
  29. GC42691 Aceclofenac ethyl ester A potential impurity found in commercial preparations of aceclofenac Aceclofenac ethyl ester Chemical Structure
  30. GC42692 Aceclofenac methyl ester

    Aceclofenac Impurity D

     A potential impurity in commercial preparations of aceclofenac Aceclofenac methyl ester Chemical Structure
  31. GC45762 Acitretin-d3

    Ro 10-1670-d3

     A neuropeptide with diverse biological activities Acitretin-d3 Chemical Structure
  32. GC40645 Actarit

    4-Acetylaminophenylacetic Acid, MS-932, NSC 170317

     Actarit, un composé antirhumatismal actif par voie orale, a le potentiel de traiter l'arthrite induite par le collagène de type II . Actarit Chemical Structure
  33. GC45375 ACTH (1-39) (trifluoroacetate salt)

    Adrenocorticotropic Hormone (1-39)

       ACTH (1-39) (trifluoroacetate salt) Chemical Structure
  34. GC45681 AKP-11 An S1P1 receptor agonist AKP-11 Chemical Structure
  35. GC26242 Alexa Fluor 594 labeled Concanavalin A

    Concanavalin Afrom Canavalla ensiformis (Jack bean), Alexa Fluor 594 ConiugateAlexa Fluor 594-ConA:Alexa Fluor 594 labeled Concan avalin A (ConA): ConAlectin(Alexa Fluor 594):

    Concanavalin ACon A, derived from Canavalia ensiformis beans, is a lectin protein (Mw 104 kDa).

     Alexa Fluor 594 labeled Concanavalin A Chemical Structure
  36. GC46867 Apremilast-d5

    APR-d5

     Apremilast D5 (CC-10004 D5) est un Apremilast marqué au deutérium. Apremilast-d5 Chemical Structure
  37. GC45790 Artesunate-d4

    Artesunic Acid-d4

     L'artésunate-d4 est un artésunate marqué au deutérium. L'artésunate est un inhibiteur de STAT-3 et de la protéine 1 exportée (EXP1). Artesunate-d4 Chemical Structure
  38. GC42856 AS-605240 (potassium salt) Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of PI at the three position to produce the second messengers PtdIns-(3,4)-P2 and PtdIns-(3,4,5)-P3. AS-605240 (potassium salt) Chemical Structure
  39. GC46895 Aurintricarboxylic Acid (ammonium salt)

    ATA

     A protein synthesis inhibitor with diverse biological activities Aurintricarboxylic Acid (ammonium salt) Chemical Structure
  40. GC49646 Aurothioglucose (hydrate)

    Gold Thioglucose

     A TrxR inhibitor Aurothioglucose (hydrate) Chemical Structure
  41. GC42877 AUY954 AUY954 is an orally bioavailable and selective agonist of the sphingosine-1-phosphate receptor 1 (S1P1; EC50 = 1.2 nM for stimulating GTPγS binding to S1P1 in CHO cells). AUY954 Chemical Structure
  42. GC42880 Avenanthramide-C methyl ester Avenanthramide-C methyl ester is an inhibitor of NF-κB activation that acts by blocking the phosphorylation of IKK and IκB (IC50 ~ 40 μM). Avenanthramide-C methyl ester Chemical Structure
  43. GC45820 Balsalazide-d4 Le balsalazide-d4 est du balsalazide marqué au deutérium. Balsalazide-d4 Chemical Structure
  44. GC91659 BDW-OH BDW-OH is an active metabolite of the STING agonist and prodrug BDW568 . BDW-OH Chemical Structure
  45. GC91379 BDW568

    BDW568 est un agoniste du stimulateur des gènes de l'interféron (STING) et une forme de prodrogue de BDW-OH.

     BDW568 Chemical Structure
  46. GC49836 Benoxaprofen

    LRCL 3794, NSC 299582

     Le bénoxaprofène (LRCL 3794) est un composé anti-inflammatoire et antipyrétique puissant et À longue durée d'action. Benoxaprofen Chemical Structure
  47. GC91947 BH400 BH400 est un agoniste du récepteur α activé par proliférateur de peroxysomes (PPARα) et un inhibiteur du stimulateur des gènes d’interféron (STING; Ci50 = 8,1 μM). BH400 Chemical Structure
  48. GC19069 BI605906 BI605906 is a novel IKKβ inhibitor with an IC50 value of 380 nM when assayed at 0.1 mM ATP. BI605906 Chemical Structure
  49. GC52326 Biotin-PEG4-LL-37 (human) (trifluoroacetate salt) A biotinylated and pegylated form of LL-37 Biotin-PEG4-LL-37 (human) (trifluoroacetate salt) Chemical Structure
  50. GC42953 BMS 345541 (trifluoroacetate salt) BMS 345541 is a cell permeable inhibitor of the IκB kinases IKKα and IKKβ (IC50s = 4 and 0.3 μM). BMS 345541 (trifluoroacetate salt) Chemical Structure
  51. GC46946 BPC 157 (acetate)

    GEPPPGKPADDAGLV, Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val

     A pentadecapeptide with diverse biological activities BPC 157 (acetate) Chemical Structure
  52. GC90705 BSP-16

    Un agoniste de STING

     BSP-16 Chemical Structure
  53. GC46983 C-170 Le C-170 (C-170) est un inhibiteur puissant et covalent de STING. C-170 Chemical Structure
  54. GC46984 C-171 Le C-171 est un inhibiteur du stimulateur des gènes de l'interféron (STING). C-171 Chemical Structure
  55. GC40570 C-178 C-178 is a covalent inhibitor of STING. C-178 Chemical Structure
  56. GC43007 C12 Galactosylceramide (d18:1/12:0)

    N-Dodecanoyl-β-D-Galactosylceramide, Galactosylceramide (d18:1/12:0), GalCer(d18:1/12:0)

     C12 Galactosylceramide is a bioactive sphingolipid. C12 Galactosylceramide (d18:1/12:0) Chemical Structure
  57. GC46985 C18 3'-sulfo Galactosylceramide-d3 (d18:1/18:0-d3)

    N-Octadecanoyl Sulfatide-d3, N-ω-CD3-Octadecanoyl-sulfatide

     A neuropeptide with diverse biological activities C18 3'-sulfo Galactosylceramide-d3 (d18:1/18:0-d3) Chemical Structure
  58. GC43076 C24 Phytosphingosine (t18:0/24:0)

    Ceramide (t18:0/24:0), Cer(t18:0/24:0), C24:0 Phytoceramide, N-Lignoceroyl Phytosphingosine, NTetracosanoyl Phytosphingosine

     C24 Phytosphingosine (t18:0/24:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis. C24 Phytosphingosine (t18:0/24:0) Chemical Structure
  59. GC43077 C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))

    (3’-sulfo)Galβ-Cer(d18:1/24:1), N-Nervonoyl Sulfatide, C24:1 Sulfatide, cis-Tetracosenoyl Sulfatide, N-Tetracosenoyl (cis-15) Sulfatide

     C24:1 3'-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids. C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) Chemical Structure
  60. GC47020 Calcium D-Glucarate (hydrate)

    Calcium D-Saccharate, D-Glucaric Acid Calcium Salt, D-Saccharic Acid Calcium Salt

     The calcium salt form of D-glucaric acid Calcium D-Glucarate (hydrate) Chemical Structure
  61. GC49147 Carboxyphosphamide

    CPCOOH, NSC 145124

     An inactive metabolite of cyclophosphamide Carboxyphosphamide Chemical Structure
  62. GC43176 CAY10575

    IKK2 Inhibitor 3, Polo-like Kinase Inhibitor 1

     CAY10575 (Composé 8) est un inhibiteur de IKK2 avec une IC50 de 0,075 μM. CAY10575 Chemical Structure
  63. GC90710 CAY10723 (hydrochloride)

    Un inhibiteur de PAD2

     CAY10723 (hydrochloride) Chemical Structure
  64. GC47054 CAY10748 A STING agonist CAY10748 Chemical Structure
  65. GC45885 Chloroquine-d5 (phosphate)

    DL-Chloroquine-d5

     An internal standard for the quantification of chloroquine Chloroquine-d5 (phosphate) Chemical Structure
  66. GC52351 Citrullinated α-Enolase (R8 + R14) (1-19)-biotin Peptide

    Citrullinated Enolase-1-biotin, α-Enolase Peptide (Citrulline Residues 8 + 14)

     A biotinylated and citrullinated α-enolase peptide Citrullinated α-Enolase (R8 + R14) (1-19)-biotin Peptide Chemical Structure
  67. GC52363 Citrullinated Histone H3 (R2 + R8 + R17) (2-22)-biotin Peptide

    Biotin-A-Cit-TKQTA-Cit-KSTGGKAP-Cit-KQLA, Biotin-AXTKQTAXKSTGGKAPXKQLA (X=Citrulline), Citrullinated Histone H3.1-biotin

    A biotinylated and citrullinated histone H3 peptide

     Citrullinated Histone H3 (R2 + R8 + R17) (2-22)-biotin Peptide Chemical Structure
  68. GC52367 Citrullinated Vimentin (G146R) (R144 + R146) (139-159)-biotin Peptide

    Biotin-GQGKS(Cit)L(Cit)DLYEEEMRELRRQ, Biotin-GQGKSXLXDLYEEEMRELRRQ (X=Citrulline), Citrullinated VIM (G146R) (R144 + R146)-biotin

     A biotinylated and citrullinated mutant vimentin peptide Citrullinated Vimentin (G146R) (R144 + R146) (139-159)-biotin Peptide Chemical Structure
  69. GC52370 Citrullinated Vimentin (R144) (139-159)-biotin Peptide

    Biotin-GQGKS(Cit)LGDLYEEEMRELRRQ, Biotin-GQGKSXLGDLYEEEMRELRRQ (X=Citrulline), Citrullinated VIM (R144)-biotin

     A biotinylated and citrullinated vimentin peptide Citrullinated Vimentin (R144) (139-159)-biotin Peptide Chemical Structure
  70. GC49680 Clobetasone Propionate

    Clobetasone 17-Propionate

     A corticosteroid Clobetasone Propionate Chemical Structure
  71. GC18572 Concanavalin A Concanavalin A appartient aux concanamycines, une famille d'antibiotiques macrolides isolés à partir de Streptomyces diastatochromogenes qui sont les inhibiteurs très actifs et sélectifs de la proton-ATPase vacuolaire (v-[H[+]]ATPase). Concanavalin A Chemical Structure
  72. GC45413 Cridanimod (sodium salt)

    10-Carboxymethyl-9-Acridanone

       Cridanimod (sodium salt) Chemical Structure
  73. GC45614 Cryogenine

    NSC 272693

     An alkaloid with anti-inflammatory activity Cryogenine Chemical Structure
  74. GC47128 CU-32 A cGAS inhibitor CU-32 Chemical Structure
  75. GC47129 CU-76 A cGAS inhibitor CU-76 Chemical Structure
  76. GC19526 Cyclic di-GMP disodium

    c-di-GMP, Cyclic diguanylate, 3',5'-Cyclic diguanylic acid

     Cyclic di-GMP disodium est une molécule de signalisation cyclique dinucléotide synthétisée par les bactéries et est un agoniste STING. Cyclic di-GMP disodium Chemical Structure
  77. GC43340 Cyclic di-IMP (sodium salt)

    c-di-IMP, Cyclic di-inosine monophosphate

     Cyclic di-IMP (sodium salt) (c-di-IMP) is a synthetic second messenger structurally related to the bacterial second messengers cyclic di-GMP and cyclic di-AMP. Cyclic di-IMP (sodium salt) Chemical Structure
  78. GC48397 Cyclic di-UMP (sodium salt)

    c-di-UMP, c-UpUp, Cyclic di-Uridine monophosphate, 3’3’-Cyclic UMP-UMP

     A pyrimidine-containing CDN Cyclic di-UMP (sodium salt) Chemical Structure
  79. GC47148 Cyclophosphamide-d4 Le cyclophosphamide-d4 est le cyclophosphamide marqué au deutérium. Le cyclophosphamide est un agent alkylant synthétique apparenté chimiquement aux moutardes azotées À activité antinéoplasique, un immunosuppresseur. Cyclophosphamide-d4 Chemical Structure
  80. GC47193 Desethyl Hydroxychloroquine-d4

    Cletoquine-d4, (±)-Desethylhydroxychloroquine-d4, DHCQ-d4

     An internal standard for the quantification of desethyl hydroxychloroquine Desethyl Hydroxychloroquine-d4 Chemical Structure
  81. GC47198 Desoximetasone-d3

    17-deoxy Dexamethasone-d3

     A neuropeptide with diverse biological activities Desoximetasone-d3 Chemical Structure
  82. GC47202 Dexamethasone-d4 A neuropeptide with diverse biological activities Dexamethasone-d4 Chemical Structure
  83. GC43444 Diclofenac Acyl-β-D-Glucuronide

    Diclofenac Glucuronide, Diclofenac-β-D-glucuronide

     Diclofenac acyl-β-D-glucuronide is an active metabolite of diclofenac and the predominant metabolite in rat. Diclofenac Acyl-β-D-Glucuronide Chemical Structure
  84. GC47212 Diclofenac amide

    Diclofenac Lactam, 1-(2,6-Dichlorophenyl)oxindole, NSC 621845

     A prodrug form of diclofenac Diclofenac amide Chemical Structure
  85. GC43447 Diclofenac methyl ester

    Methanol Diclofenac ester

     Diclofenac methyl ester is a hydrophobic prodrug form of the non-steroidal anti-inflammatory drug (NSAID) diclofenac. Diclofenac methyl ester Chemical Structure
  86. GC47213 Diclofenac-d4 An internal standard for the quantification of diclofenac Diclofenac-d4 Chemical Structure
  87. GC40867 Diflorasone Diacetate

    U-34865

     Le diacétate de diflorasone est un composé stéroÏdien anti-inflammatoire utilisé comme agent local ou topique. Diflorasone Diacetate Chemical Structure
  88. GC43494 DL-threo-PDMP (hydrochloride) DL-threo PDMP is a mixture of ceramide analogs that contains two of the four possible stereoisomers of PDMP : D-threo (1R,2R) and L-threo (1S,2S) PDMP. DL-threo-PDMP (hydrochloride) Chemical Structure
  89. GC52334 ENPP1 Inhibitor 4e

    cGAMP-compound 4e

     An ENPP1 inhibitor ENPP1 Inhibitor 4e Chemical Structure
  90. GC52303 Ethyl Mycophenolate A potential impurity found in commercial preparations of mycophenolate mofetil Ethyl Mycophenolate Chemical Structure
  91. GC47321 Etifoxine-13C-d3 A neuropeptide with diverse biological activities Etifoxine-13C-d3 Chemical Structure
  92. GC47323 Etofenamate-d4 An internal standard for the quantification of etofenamate Etofenamate-d4 Chemical Structure
  93. GC91921 Fenclofenac

    RX-67408

     Fenclofenac est un anti - inflammatoire non stéroïdien (ains) et un inhibiteur de la Cox (IC50 de 7 et 4 μm pour Cox - 1 et Cox - 2, respectivement). Fenclofenac Chemical Structure
  94. GC91909 Fenoprofen-13C6 (sodium salt hydrate) Fenoprofen-13C6 (sodium salt hydrate) destiné à être utilisé comme étalon interne pour la quantification du fénoprofène par GC ou LC - MS. Fenoprofen-13C6 (sodium salt hydrate) Chemical Structure
  95. GC40565 Feprazone La féprazone (DA2370 ; prénazone), un analogue de la phénylbutazone, est un agent anti-inflammatoire non stéroÏdien ayant des activités analgésiques et antipyrétiques. Feprazone Chemical Structure
  96. GC46148 Filgotinib-d4

    GLPG0634-d4

     Le filgotinib-d4 (GLPG0634-d4) est le filgotinib marqué au deutérium. Le filgotinib (GLPG0634) est un inhibiteur sélectif de JAK1 avec une IC50 de 10 nM, 28 nM, 810 nM et 116 nM pour JAK1, JAK2, JAK3 et TYK2, respectivement. Filgotinib-d4 Chemical Structure
  97. GC47366 Flurbiprofen-d3 An internal standard for the quantification of flurbiprofen Flurbiprofen-d3 Chemical Structure
  98. GC49074 Forphenicine A bacterial metabolite and an inhibitor of alkaline phosphatase Forphenicine Chemical Structure
  99. GC52487 Ganglioside GM4 (chicken egg) (ammonium salt)

    Ganglioside G7, Monosialoganglioside GM4

     A sphingolipid Ganglioside GM4 (chicken egg) (ammonium salt) Chemical Structure
  100. GC64257 Gelsevirine La gelsevirine est le principal alcaloÏde de Gelsemium elegans avec de puissants effets anxiolytiques. Gelsevirine Chemical Structure
  101. GC20007 Ginsenoside CK

    Ginsenoside Compound K, Ginsenoside IH901; Compound K

     Ginsenoside CK, une ginsénoside secondaire biotransformée à partir de ginsénosides majeurs, est plus biodisponible et soluble que des ginsénosides parents et revêt une grande importance. Ginsenoside CK Chemical Structure

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