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Accueil >> Signaling Pathways >> Immunology/Inflammation >> Innate Immunity

Innate Immunity

Products for  Innate Immunity

  1. Cat.No. Nom du produit Informations
  2. GC45206 α-GalCer analog 8

    α-Galactosylceramide analog 8

    α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide.

     α-GalCer analog 8 Chemical Structure
  3. GC48292 α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

    α-Melanocyte-stimulating Hormone, Ac-SYSMEHFRWGKPV-NH2

     α-MSH (α-Melanocyte-Stimulating Hormone) TFA, un neuropeptide endogène, est un agoniste endogène du récepteur 4 de la mélanocortine (MC4R) avec des activités anti-inflammatoires et antipyrétiques. α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) Chemical Structure
  4. GC41499 α-Phellandrene

    p-Mentha-1,5-diene, (±)-α-Phellandrene

     α-Phellandrene is a cyclic monoterpene that has been found in various plants, including Cannabis, and has diverse biological activities. α-Phellandrene Chemical Structure
  5. GC48920 β-Carboline-1-carboxylic Acid

    1-Formic Acid-β-carboline

     An alkaloid with diverse biological activities β-Carboline-1-carboxylic Acid Chemical Structure
  6. GC48298 β-Defensin-2 (human) (trifluoroacetate salt)

    hBD-2

     An antimicrobial peptide β-Defensin-2 (human) (trifluoroacetate salt) Chemical Structure
  7. GC45230 β-Defensin-3 (human) (trifluoroacetate salt)

    hBD-3

     β-Defensin-3 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. β-Defensin-3 (human) (trifluoroacetate salt) Chemical Structure
  8. GC45231 β-Defensin-4 (human) (trifluoroacetate salt)

    hBD-4 (human)

     β-Defensin-4 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. β-Defensin-4 (human) (trifluoroacetate salt) Chemical Structure
  9. GC72061 β-Phellandrene β-Phellandrene obtenu à partir d'os de roche. β-Phellandrene Chemical Structure
  10. GC52010 (±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic Acid

    αHYA, (±)-10-hydroxy-12(Z),15(Z)-ODE

     An oxylipin gut microbiota metabolite (±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic Acid Chemical Structure
  11. GC91298 (±)-Linalool-d3

    Un standard interne pour la quantification du (±)-linalol.

     (±)-Linalool-d3 Chemical Structure
  12. GC40466 (±)11(12)-EET

    (±)11,12-EpETrE

     (±)11(12)-EET est un inhibiteur de l'inflammasome NLRP3. (±)11(12)-EET Chemical Structure
  13. GC45922 (±)11(12)-EET-d11 methyl ester

    (±)11,12-EpETrE-d11 methyl ester

     A neuropeptide with diverse biological activities (±)11(12)-EET-d11 methyl ester Chemical Structure
  14. GC40802 (±)12(13)-DiHOME

    Isoleukotoxin diol

    (±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME, a cytochrome P450-derived epoxide of linoleic acid also known as isoleukotoxin.

     (±)12(13)-DiHOME Chemical Structure
  15. GC46256 (±)12(13)-DiHOME-d4

    Isoleukotoxin diold4

     A neuropeptide with diverse biological activities (±)12(13)-DiHOME-d4 Chemical Structure
  16. GC41288 (±)17(18)-EpETE-Ethanolamide

    17,18-EEQ-EA, (±)17,18-EEQ-Ethanolamide, (±)17(18)-EpETE-EA, 17,18-epoxy-Eicosatetraenoic Acid Ethanolamide

     (±)17(18)-EpETE-Ethanolamide is an ω-3 endocannabinoid epoxide. (±)17(18)-EpETE-Ethanolamide Chemical Structure
  17. GC40362 (±)18-HEPE (±)18-HEPE is produced by non-enzymatic oxidation of EPA. (±)18-HEPE Chemical Structure
  18. GC41655 (±)19(20)-EDP Ethanolamide

    19,20-DHEA epoxide, 19,20-epoxy Docosapentaenoic Acid Ethanolamide, 19,20-EDP-EA, 19,20-EDP epoxide

     (±)19(20)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 108 and 280 nM for CB1 and CB2, respectively). (±)19(20)-EDP Ethanolamide Chemical Structure
  19. GC40801 (±)9(10)-DiHOME

    Leukotoxin diol

     (±)9(10)-DiHOME est le racémate de 9,10-DiHOME. (±)9(10)-DiHOME Chemical Structure
  20. GC40540 (±)9(10)-EpOME

    Coronaric Acid, (±)9,10EODE, Leukotoxin

     (±)9(10)-EpOME is the 9,10-cis epoxide of linoleic acid, generated by neutrophils during the oxidative burst. (±)9(10)-EpOME Chemical Structure
  21. GC40218 (-)-Epigallocatechin Gallate-d3/d4

    EGCG-d3/d4

     (-)-Epigallocatechin gallate-d3/d4 is intended for use as an internal standard for the quantification of (-)-epigallocatechin gallate by GC- or LC-MS. (-)-Epigallocatechin Gallate-d3/d4 Chemical Structure
  22. GC45272 (-)-Rasfonin

    TT-1

     La (-)-Rasfonine est un métabolite secondaire fongique et inhibe les petites protéines G Ras. La (-)-Rasfonine induit l'apoptose, la nécrose et l'autophagie dans les cellules ACHN (une lignée cellulaire de carcinome rénal). (-)-Rasfonin Chemical Structure
  23. GC41712 (R)-3-hydroxy Myristic Acid

    (R)-3-hydroxy Tetradecanoic Acid

     Lipopolysaccharides (LPS) are components of the cell walls of Gram-negative bacteria. (R)-3-hydroxy Myristic Acid Chemical Structure
  24. GC18773 (Rac)-Benpyrine La (Rac)-benpyrine, un racémate de la benpyrine, est un puissant inhibiteur du TNF-α actif par voie orale. (Rac)-Benpyrine Chemical Structure
  25. GC46352 (S)-DO271 An inactive control for DO264 (S)-DO271 Chemical Structure
  26. GC41740 (S)-p38 MAPK Inhibitor III

    (S)-p38 MAP Kinase Inhibitor III, (S)-p38 Mitogen-activated Protein Kinase Inhibitor III

     (S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 μM in vitro). (S)-p38 MAPK Inhibitor III Chemical Structure
  27. GC19824 (±)-Pinocembrin

    (+)-Pinocembrin, Dihydrochrysin, NSC 279005

     La (±)-pinocembrine ((±)-5,7-dihydroxyflavanone) est un ligand du GPR120 capable de favoriser la cicatrisation des plaies dans la lignée cellulaire HaCaT. (±)-Pinocembrin Chemical Structure
  28. GC49768 1,1’-Ethylidene-bis-(L-tryptophan)

    Peak 97 Contaminant, Peak E Contaminant, Peak E Substance

     A potential impurity found in commercial preparations of L-tryptophan 1,1’-Ethylidene-bis-(L-tryptophan) Chemical Structure
  29. GC41855 1,3-Distearoyl-2-Oleoyl-rac-glycerol

    1,3-Distearin-2-Olein, TG(18:0/18:1/18:0)

     1,3-Distearoyl-2-oleoyl-rac-glycerol is a triacylglycerol that contains stearic acid at the sn-1 and sn-3 positions and oleic acid at the sn-2 position. 1,3-Distearoyl-2-Oleoyl-rac-glycerol Chemical Structure
  30. GC49294 1-(4-Chlorobenzhydryl)piperazine

    N-(p-Chlorobenzhydryl)-piperazine, Norchlorcyclizine, NSC 86164

     An inactive metabolite of meclizine and chlorcyclizine 1-(4-Chlorobenzhydryl)piperazine Chemical Structure
  31. GC41986 1-Arachidonoyl Lysophosphatidic Acid (ammonium salt)

    1-Arachidonoyl LPA, 1-Arachidonoyl-sn-glycero-3-phosphate, 1-Eicosatetraenoyl-sn-glycero-3-PA, 20:4 Lyso PA, LPA(20:4), PA(20:4/0:0)

    1-Arachidonoyl lysophosphatidic acid is a phospholipid containing arachidonic acid at the sn-1 position.

     1-Arachidonoyl Lysophosphatidic Acid (ammonium salt) Chemical Structure
  32. GC46481 1-Hydroxyphenazine

    Hemipyocyanine, NSC 88882

     A P. aeruginosa virulence factor 1-Hydroxyphenazine Chemical Structure
  33. GC41998 1-Methyl-4-imidazoleacetic Acid (hydrochloride)

    Methylimidazoleacetic Acid, MIMA, MIAA

     1-Methyl-4-imidazoleacetic acid (MIMA) is a stable metabolite of histamine that is produced by the oxidation of the primary metabolite, N-methylhistamine. 1-Methyl-4-imidazoleacetic Acid (hydrochloride) Chemical Structure
  34. GC19514 1-Methyl-L-tryptophan

    NSC 77678, L-1-Methyltryptophan, 1-L-MT, L-1MT

     1-Methyl-L-tryptophan Chemical Structure
  35. GC40910 1-Oleoyl-2-hydroxy-sn-glycero-3-PE

    18:1 LPE, 18:1 Lyso-PE, 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine

     1-Oleoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine. 1-Oleoyl-2-hydroxy-sn-glycero-3-PE Chemical Structure
  36. GC42026 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC

    1-Hexadecanoyl-sn-glycero-3-Phosphatidylcholine, 1-Hexadecanoyl-sn-glycero-3-Phosphocholine, 1-Hexadecanoyl-sn-glycerol-3-Phosphorylcholine, Lyso-PC, 1-Palmitoyl-sn-glycero-3-Phosphocholine, PC(16:0/0:0), 16:0/0:0-PC

     Le 1-palmitoyl-2-hydroxy-sn-glycéro-3-PC est un LPC gonadique abondant (lysophosphatidylcholine). 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC Chemical Structure
  37. GC42035 1-Palmitoyl-2-Stearoyl-3-Oleoyl-rac-glycerol

    1-Palmitin-2-Stearin-3-Olein, TG(16:0/18:0/18:1)

     1-Palmitoyl-2-stearoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains palmitic, stearic, and oleic acid at the sn-1, sn-2, and sn-3 positions, respectively. 1-Palmitoyl-2-Stearoyl-3-Oleoyl-rac-glycerol Chemical Structure
  38. GC46490 1-Palmitoyl-d3-2-hydroxy-sn-glycero-3-PC

    1-Hexadecanoyl-sn-glycero-3-Phosphatidylcholine-d3, 1-Hexadecanoyl-sn-glycero-3-Phosphocholine-d3, LPC-d3, 16:0/0:0(d3) Lyso-PC, 1-Palmitoyl-sn-glycero-3-Phosphocholine-d3, PC(16:0/0:0)-d3, 16:0/0:0-PC-d3

     A neuropeptide with diverse biological activities 1-Palmitoyl-d3-2-hydroxy-sn-glycero-3-PC Chemical Structure
  39. GC45693 1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PC

    1-Hexadecanoyl-d9-sn-glycero-3-Phosphatidylcholine, 1-Hexadecanoyl-d9-sn-glycero-3-Phosphocholine, 16:0(d9) Lyso-PC, PC(16:0-d9/0:0), 16:0-d9/0:0-PC

     A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications 1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PC Chemical Structure
  40. GC49730 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11

    15(S)-HETE-SAPE-d11, 15(S)-Hydroxyeicosatetraenoic Acid-SAPE-d11, 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-Phosphatidylethanolamine-d11

     An internal standard for the quantification of 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11 Chemical Structure
  41. GC41331 1-Stearoyl-2-hydroxy-sn-glycero-3-PC

    C18:0-PC, Lyso-PC, 1-Octadecanoyl-2-hydroxy-sn-glycero-3-phosphatidylcholine, PC(18:0/0:0), 1-Stearoyl-2-hydroxy-sn-glycero-3-Phosphocholine, 1-Stearoyl-2-lyso-sn-glycero-3-PC

     1-Stearoyl-2-hydroxy-sn-glycero-3-PC is a saturated 18:0 lysophosphatidylcholine found in plasma and oxidized LDL that is thought to play a role in inflammatory diseases and atherosclerosis. 1-Stearoyl-2-hydroxy-sn-glycero-3-PC Chemical Structure
  42. GC46498 1-Stearoyl-d35-2-hydroxy-sn-glycero-3-PC

    S-Lyso-PC-d35, 1-Stearoyl-d35-2-hydroxy-sn-glycero-3-Phosphocholine, 1-Stearoyl-d35-2-lyso-sn-glycero-3-PC

     An internal standard for the quantification of 1-stearoyl-2-hydroxy-sn-glycero-3-PC 1-Stearoyl-d35-2-hydroxy-sn-glycero-3-PC Chemical Structure
  43. GC40971 10(S),17(S)-DiHDHA

    10(S),17(S)-DiHDoHE, PDX, Protectin DX

     La 10(S),17(S)-DiHDHA (également connue sous le nom de neuroprotectine D1 lorsqu'elle est produite dans les tissus neuronaux) est un acide gras dihydroxy dérivé du DHA qui présente de puissantes activités protectrices et anti-inflammatoires. 10(S),17(S)-DiHDHA Chemical Structure
  44. GC41875 11(Z),14(Z)-Eicosadienoic Acid methyl ester 11(Z),14(Z)-Eicosadienoic acid methyl ester is a more lipid soluble form of the ω-6 C20-2 fatty acid 11(Z),14(Z)-eicosadienoic acid, a naturally occurring PUFA. 11(Z),14(Z)-Eicosadienoic Acid methyl ester Chemical Structure
  45. GC41144 11-trans Leukotriene C4

    11trans LTC4

     11-trans Leukotriene C4 (11-trans LTC4) is a C-11 double bond isomer of LTC4. 11-trans Leukotriene C4 Chemical Structure
  46. GC52343 113-O12B An ionizable cationic lipidoid 113-O12B Chemical Structure
  47. GC18637 11β-Prostaglandin F2α

    9α,11βPGF2α, 11βPGF2α, 11epi PGF2α

    11β-Prostaglandin F2α (11β-PGF2α) is the primary plasma metabolite of PGD2 in vivo.

     11β-Prostaglandin F2α Chemical Structure
  48. GC40447 12(R)-HETE

    12(R)-Hydroxyeicosatetraenoic Acid

     Biosynthesis of 12(R)-HETE in invertebrates is via lipoxygenation of arachidonic acid. 12(R)-HETE Chemical Structure
  49. GC41123 12-epi Leukotriene B4

    12epi LTB4

     Leukotriene B4 (LTB4) compounds are produced by both enzymatic and non-enzymatic processes. 12-epi Leukotriene B4 Chemical Structure
  50. GC41096 12-oxo Leukotriene B4

    12keto LTB4, 12oxo LTB4

     Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-LO pathway. 12-oxo Leukotriene B4 Chemical Structure
  51. GC49912 13C20,15N10-Cyclic di-GMP (sodium salt)

    13C20,15N10-c-di-GMP, 13C20,15N10-Cyclic diguanylate, 13C20,15N10-3’,5’-Cyclic diguanylic Acid

     An internal standard for the quantification of cyclic di-GMP 13C20,15N10-Cyclic di-GMP (sodium salt) Chemical Structure
  52. GC41100 14,15-dehydro Leukotriene B4

    14,15dehydro LTB4

     Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway. 14,15-dehydro Leukotriene B4 Chemical Structure
  53. GC41145 14,15-Leukotriene C4

    Eoxin C4, EXC4, 14,15LTC4

     Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. 14,15-Leukotriene C4 Chemical Structure
  54. GC41148 14,15-Leukotriene D4

    Eoxin D4, EXD4, 14,15-LTD4

     14,15-Leukotriene D4 (14,15-LTD4) is a member of an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-lipoxygenases (15- and 12-LOs) on arachidonic acid via 15-HpETE and 14,15-LTA4 intermediates. 14,15-Leukotriene D4 Chemical Structure
  55. GC41150 14,15-Leukotriene E4

    Eoxin E4, EXE4, 14,15LTE4

     Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. 14,15-Leukotriene E4 Chemical Structure
  56. GC41164 15(R)-15-methyl Prostaglandin D2

    15(R)15methyl PGD2

     15(R)-15-methyl Prostaglandin D2 (15(R)-15-methyl PGD2) is a metabolically stable synthetic analog of PGD2. 15(R)-15-methyl Prostaglandin D2 Chemical Structure
  57. GC41415 15(R)-Lipoxin A4

    AT-Lipoxin A4

    Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and function.

     15(R)-Lipoxin A4 Chemical Structure
  58. GC40451 15(S)-HETE

    15(S)-Hydroxyeicosatetraenoic Acid

     15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. 15(S)-HETE Chemical Structure
  59. GC40452 15(S)-HETE MaxSpec® Standard 15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. 15(S)-HETE MaxSpec® Standard Chemical Structure
  60. GC41102 15-deoxy-δ12,14-Prostaglandin D2

    15deoxyΔ12,14PGD2

     15-deoxy-δ12,14-PGD2 is a synthetic analog of PGD2 and a potential precursor to the PPARγ ligand 15-deoxy-δ12,14-PGJ2. 15-deoxy-δ12,14-Prostaglandin D2 Chemical Structure
  61. GC46443 15-deoxy-δ12,14-Prostaglandin D2-d4

    15-deoxy-Δ12,14-PGD2-d4

     A neuropeptide with diverse biological activities 15-deoxy-δ12,14-Prostaglandin D2-d4 Chemical Structure
  62. GC46444 15-deoxy-δ12,14-Prostaglandin D2-d9

    15-deoxy-Δ12,14-PGD2-d9

     A neuropeptide with diverse biological activities 15-deoxy-δ12,14-Prostaglandin D2-d9 Chemical Structure
  63. GC40606 15-keto Prostaglandin E2 MaxSpec® Standard 15-keto Prostaglandin E2 (15-keto PGE2) is a metabolite of PGE2 formed by 15-hydroxy PGDH. 15-keto Prostaglandin E2 MaxSpec® Standard Chemical Structure
  64. GC46449 15-keto Prostaglandin E2-d4

    15-keto PGE2-d4, 15-oxo PGE2-d4

     A neuropeptide with diverse biological activities 15-keto Prostaglandin E2-d4 Chemical Structure
  65. GC46450 15-keto Prostaglandin E2-d9

    15-keto PGE2-d9, 15-oxo PGE2-d9

     A neuropeptide with diverse biological activities 15-keto Prostaglandin E2-d9 Chemical Structure
  66. GC49178 17(R)-Protectin D1

    Aspirin-triggered Protectin D1, 17-epi Neuroprotectin D1, 17(R)-Neuroprotectin D1, 17(R)-NPD1, 17(R)-PD1, 17-epi Protectin D1

     An aspirin-triggered epimer of protectin D1 17(R)-Protectin D1 Chemical Structure
  67. GC41951 17(R)-Resolvin D1

    Aspirin-triggered Resolvin D1

    Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid.

     17(R)-Resolvin D1 Chemical Structure
  68. GC41227 17(R)-Resolvin D1 methyl ester

    AspirintriggeredResolvin D1 methyl ester, ATRvD1 methyl ester, 17epiResolvin D1 methyl ester, 17(R)RvD1 methyl ester

     17(R)-Resolvin D1 (17(R)-RvD1) is an aspirin-triggered epimer of RvD1 that reduces human polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, with equipotency to RvD1 (EC50 = ~30 nM). 17(R)-Resolvin D1 methyl ester Chemical Structure
  69. GC45307 17(R)-Resolvin D3

    Aspirin-triggered Resolvin D3, 17-epi-Resolvin D3, AT-RvD3, 17(R)-RvD3

       17(R)-Resolvin D3 Chemical Structure
  70. GC41208 17(S)-HDHA

    17(S)hydroxy Docosahexaenoic Acid, 17(S)HDoHE

     17(S)-HDHA is a primary mono-oxygenation product of docosahexaenoic acid in human whole blood, human leukocytes, and mouse brain. 17(S)-HDHA Chemical Structure
  71. GC46048 17(S)-HDHA-d5

    17(S)-hydroxy Docosahexaenoic Acid-d5, 17(S)-HDoHE-d5

     A neuropeptide with diverse biological activities 17(S)-HDHA-d5 Chemical Structure
  72. GC40975 17(S)-HpDHA

    17(S)hydroperoxy Docosahexaenoic Acid, 17(S)HpDoHE

     17(S)-HpDHA is a mono-oxygenation product of docosahexaenoic acid in human whole blood, human leukocytes, human glial cells, and mouse brain. 17(S)-HpDHA Chemical Structure
  73. GC41160 1a,1b-dihomo Prostaglandin E2

    1a,1b-dihomo PGE2

     1a,1b-dihomo Prostaglandin E2 (PGE2) is a rare polyunsaturated fatty acid first identified in extracts of sheep vesicular gland microsomes, known to contain COX, incubated with adrenic acid. 1a,1b-dihomo Prostaglandin E2 Chemical Structure
  74. GC90803 2',3'-Dideoxyadenosine-5'-O-triphosphate (sodium salt)

    Un inhibiteur de la transcriptase inverse et un métabolite actif de ddA et ddI.

     2',3'-Dideoxyadenosine-5'-O-triphosphate (sodium salt) Chemical Structure
  75. GC42080 2'2'-cGAMP (sodium salt)

    Adenosine-Guanosine 2’,2’-cyclic monophosphate, cGAMP(2’-5’), 2’,2’-Cyclic GMP-AMP

     2'2'-cGAMP is a synthetic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds. 2'2'-cGAMP (sodium salt) Chemical Structure
  76. GC42123 2-Aminopurine (hydrochloride)

    2-AP

     La 2-aminopurine (chlorhydrate) est un analogue fluorescent de la guanosine. 2-Aminopurine (hydrochloride) Chemical Structure
  77. GC42135 2-chloro Palmitic Acid

    2-ClHA, 2-CLPA

     L'acide 2-chloro palmitique, un médiateur lipidique inflammatoire, interfère avec la palmitoylation des protéines, induit des marqueurs de stress ER, réduit la teneur en ATP ER et active la transcription et la sécrétion d'IL-6 ainsi que d'IL-8.2-chloro L'acide palmitique perturbe la mitochondrie potentiel membranaire et induit le clivage de la procaspase-3 et de la PARP. L'acide palmitique 2-chloro peut traverser la barrière hémato-encéphalique (BBB) et compromettre les fonctions ER et mitochondriales dans la lignée cellulaire endothéliale du cerveau humain hCMEC/D3. 2-chloro Palmitic Acid Chemical Structure
  78. GC42136 2-chloro Stearic Acid

    α-Chlorostearic acid

     2-chloro Stearic acid is a bioactive fatty acid that accumulates in primary human monocytes and neutrophils as well as murine neutrophils stimulated with phorbol 12-myristate 13-acetate. 2-chloro Stearic Acid Chemical Structure
  79. GC42082 20-carboxy Leukotriene B4

    20carboxy LTB4

     20-carboxy LTB4 is a metabolite of LTB4 in human neutrophils. 20-carboxy Leukotriene B4 Chemical Structure
  80. GC41421 20-hydroxy Leukotriene B4

    20hydroxy LTB4

     20-hydroxy LTB4 is a metabolite of LTB4 in human neutrophils. 20-hydroxy Leukotriene B4 Chemical Structure
  81. GC40571 24(S),25-epoxy Cholesterol

    24(S)-24,25-EC

    24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.

     24(S),25-epoxy Cholesterol Chemical Structure
  82. GC48482 28-Acetylbetulin

    28-acetoxy Betulin, 28-O-Acetylbetulin, C-28-Acetylbetulin

     A lupane triterpenoid with anti-inflammatory and anticancer activities 28-Acetylbetulin Chemical Structure
  83. GC49122 3′-deoxy Thymidine

    2’,3’-Dideoxythymidine, d2T, ddThd

     An antiviral nucleoside analog 3′-deoxy Thymidine Chemical Structure
  84. GC42242 3'-sulfo Galactosylsphingosine (ammonium salt)

    Lyso 3’-sulfo Galactosylceramide, Lyso-Sulfatide, Sphingosine-1-Galactoside-3-Sulfate, Sulfogalactosylsphingosine

     3'-sulfo Galactosylsphingosine is a form of sulfatide that is lacking the fatty acyl group. 3'-sulfo Galactosylsphingosine (ammonium salt) Chemical Structure
  85. GC46583 3-Amino-2,6-Piperidinedione

    α-Aminoglutarimide, 3-Aminoglutarimide, Glutamimide

     An active metabolite of (±)-thalidomide 3-Amino-2,6-Piperidinedione Chemical Structure
  86. GC42251 3-Bromotyrosine (trifluoroacetate salt)

    3-bromo-Tyr

     3-Bromotyrosine is a product of protein oxidation found after activation of eosinophils during an allergic response. 3-Bromotyrosine (trifluoroacetate salt) Chemical Structure
  87. GC42252 3-Bromotyrosine-13C9,15N (trifluoroacetate salt)

    3-bromo-Tyr-13C9,15N

     3-Bromotyrosine-13C9,15N is intended for use as an internal standard for the quantification of 3-bromotyrosine by GC- or LC-MS. 3-Bromotyrosine-13C9,15N (trifluoroacetate salt) Chemical Structure
  88. GC45354 4β-Hydroxywithanolide E

    NSC 212509

     4β-Hydroxywithanolide E, isolé de Physalis peruviana L. 4β-Hydroxywithanolide E Chemical Structure
  89. GC45931 4(S),11(R)-DiHDoHE A neuropeptide with diverse biological activities 4(S),11(R)-DiHDoHE Chemical Structure
  90. GC91680 4-Acetamido Antipyrine

    4-AAAP,NSC 331807

     4-Acetamido antipyrine (4-AAAP) is an active metabolite of the non-opioid analgesic and antipyretic prodrug metamizole . 4-Acetamido Antipyrine Chemical Structure
  91. GC42338 4-Aminobenzoic Acid hydrazide

    4ABAH, Myeloperoxidase Inhibitor 1, NSC 640

     L'hydrazide d'acide 4-aminobenzoÏque est un inhibiteur irréversible de la myéloperoxydase MPO avec une IC50 de 0,3 μM. 4-Aminobenzoic Acid hydrazide Chemical Structure
  92. GC46630 4-CPPC A MIF-2 inhibitor 4-CPPC Chemical Structure
  93. GC42369 4-Deoxypyridoxine (hydrochloride)

    4-Deoxypyridoxine, DOP, 4-DPD

     4-Deoxypyridoxine (4-DPD) is a vitamin B6 antimetabolite with diverse biological activities. 4-Deoxypyridoxine (hydrochloride) Chemical Structure
  94. GC42374 4-epi-Chlortetracycline (hydrochloride)

    7-chloro-2-Naphthacenecarboxamide

     Chlortetracycline is an analog of tetracycline, a broad spectrum antibiotic. 4-epi-Chlortetracycline (hydrochloride) Chemical Structure
  95. GA20418 4-Hydroxy-hippuric acid

    p-Hydroxyhippuric Acid; para-Hydroxyhippuric Acid

     Polyphenol metabolite. 4-Hydroxy-hippuric acid Chemical Structure
  96. GC92085 4-O10b1 4-O10b1 est un lipide cationique ionisable (pKa = 5,148) qui a été utilisé dans la génération de nanoparticules lipidiques (LNP) pour la délivrance de siRNA in vitro et in vivo. 4-O10b1 Chemical Structure
  97. GC46673 4-octynyl Itaconate

    ITalk

     L'itaconate de 4-octynyle (ITalk) est une sonde bioorthogonale spécifique pour le profilage chimioprotéomique quantitatif et spécifique au site de l'itaconation dans les cellules vivantes. 4-octynyl Itaconate Chemical Structure
  98. GC48381 5'-pApA (sodium salt)

    c-di-AMP Control, Cyclic di-AMP Negative Control

     A linearized form of cyclic di-AMP 5'-pApA (sodium salt) Chemical Structure
  99. GC48375 5'-pGpG (sodium salt)

    c-di-GMP Control, Cyclic di-GMP Negative Control

     A linearized form of cyclic di-GMP 5'-pGpG (sodium salt) Chemical Structure
  100. GC41126 5(S),12(S)-DiHETE 5(S),12(S)-DiHETE is a natural bioactive lipid derived from arachidonic acid. 5(S),12(S)-DiHETE Chemical Structure
  101. GC41127 5(S),15(S)-DiHETE Le 5(S),15(S)-DiHETE est un intermédiaire « activé », inhibe l'agrégation plaquettaire avec une IC50 de 1,3 μM. 5(S),15(S)-DiHETE Chemical Structure

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