Accueil>>Signaling Pathways>> Proteases>> Endogenous Metabolite>>(S)-3,4-Dihydroxybutyric acid lithium hydrate

(S)-3,4-Dihydroxybutyric acid lithium hydrate

Catalog No.GC64473

L'acide (S)-3,4-dihydroxybutyrique (hydrate de lithium) est un métabolite urinaire humain normal qui est excrété en concentration accrue chez les patients présentant un déficit en semialdéhyde succinique déshydrogénase (SSADH).

Products are for research use only. Not for human use. We do not sell to patients.

(S)-3,4-Dihydroxybutyric acid lithium hydrate Chemical Structure

Taille Prix Stock Qté
5 mg
135,00 $US
En stock
10 mg
216,00 $US
En stock
25 mg
432,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

(S)-3,4-Dihydroxybutyric acid (lithium hydrate) is a normal human urinary metabolite that is excreted in increased concentration in patients with succinic semialdehyde dehydrogenase (SSADH) deficiency[1].

[1]. Shinka T, et al. Rapid and sensitive detection of urinary 4-hydroxybutyric acid and its related compounds by gas chromatography-mass spectrometry in a patient with succinic semialdehyde dehydrogenase deficiency. J Chromatogr B Analyt Technol Biomed Life Sci. 2002 Aug 25;776(1):57-63.

Chemical Properties

Cas No. SDF Download SDF
Formula C4H9LiO5 M.Wt 144.05
Solubility Water : 125 mg/mL (867.75 mM; Need ultrasonic) Storage 4°C, away from moisture
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 6.942 mL 34.7102 mL 69.4203 mL
5 mM 1.3884 mL 6.942 mL 13.8841 mL
10 mM 0.6942 mL 3.471 mL 6.942 mL
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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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