(S)-Verapamil D7 hydrochloride (Synonyms: (S)-(-)-Verapamil D7 hydrochloride) |
| Catalog No.GC60425 |
Le chlorhydrate de (S)-vérapamil D7 (chlorhydrate de (S)-(-)-vérapamil D7) est un chlorhydrate de (S)-vérapamil marqué au deutérium. Le chlorhydrate de (S)-vérapamil (chlorhydrate de S(-)-vérapamil) inhibe le transport des leucotriènes C4 (LTC4) et de la calcéine par MRP1. Le chlorhydrate de (S)-vérapamil entraÎne la mort des cellules tumorales potentiellement résistantes.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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(S)-Verapamil D7 hydrochloride ((S)-(-)-Verapamil D7 hydrochloride) is a deuterium labeled (S)-Verapamil hydrochloride. (S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells[1][2].
[1]. Perrotton T, et al. (R)- and (S)-verapamil differentially modulate the multidrug-resistant protein MRP1. J Biol Chem. 2007 Oct 26;282(43):31542-8. Epub 2007 Jul 22. [2]. Tannergren C, et al. St John's wort decreases the bioavailability of R- and S-verapamil through induction of the first-pass metabolism. Clin Pharmacol Ther. 2004 Apr;75(4):298-309.
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