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Ganglioside GD2 Mixture (bovine buttermilk) (ammonium salt) (Synonyms: Disialoganglioside GD2 Mixture, Ganglioside GD2, Disialo Mixture)

Catalog No.GC49490

A semi-synthetic mixture of ganglioside GD2

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Ganglioside GD2 Mixture (bovine buttermilk) (ammonium salt) Chemical Structure

Cas No.: N/A

Size Price Stock Qty
500 µg
$1,166.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

Ganglioside GD2 is a glycosphingolipid that contains two sialic acid residues linked to an inner galactose unit. It is frequently expressed on tumor cells of neuroectodermal origin, including neuroblastomas.1 Ganglioside GD2 Mixture (bovine buttermilk) is a semi-synthetic mixture of ganglioside GD2 produced from buttermilk and is thus free from potential contamination with transmissible spongiform encephalopathies (TSE). This mixture contains ganglioside GD2 molecular species with fatty acyl chains of variable lengths.

1.Barker, E.L., Mueller, B.M., Handgretinger, R., et al.Effect of a chimeric anti-ganglioside GD2 antibody on cell-mediated lysis of human neuroblastoma cellsCancer Res.51(1)144-149(1991)

Chemical Properties

Cas No. N/A SDF Download SDF
Synonyms Disialoganglioside GD2 Mixture, Ganglioside GD2, Disialo Mixture
Canonical SMILES O[C@@H]1[C@@H](O)[C@H](OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC([R])=O)O[C@H](CO)[C@@]1([H])O[C@@H]2O[C@H](CO)[C@H](O[C@@]3([H])[C@H](NC(C)=O)[C@@H](O)[C@@H](O)[C@@H](CO)O3)[C@H](O[C@@]4(C([O-])=O)O[C@]([C@H](O)[C@@H](CO)O[C@@]5(C([O-])=O)O[C@]([C@H](O)[C@H](O)CO)([H])[C@H](NC(C)=O)[C@@H](O)C5)([H])[C@H](NC(C)=O)[C@@H](O)C4)[C@H]2O.[NH4+].[NH4+]
Formula C83H148N4O34 • 2NH4 (for tricosanoyl) M.Wt 1746.1
Solubility Chloroform:Methanol:Water (2:1:0.1): soluble Storage -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 0.5727 mL 2.8635 mL 5.727 mL
5 mM 0.1145 mL 0.5727 mL 1.1454 mL
10 mM 0.0573 mL 0.2864 mL 0.5727 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Reviews

Review for Ganglioside GD2 Mixture (bovine buttermilk) (ammonium salt)

Average Rating: 5 ★★★★★ (Based on Reviews and 15 reference(s) in Google Scholar.)

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