JAK3 covalent inhibitor-1 |
| Catalog No.GC36365 |
JAK3 covalent inhibitor-1 is a potent and selective janus kinase 3 (JAK3) covalent inhibitor with an IC50 of 11 nM and shows 246-fold selectivity vs other JAKs.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2300106-50-5
Sample solution is provided at 25 µL, 10mM.
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JAK3 covalent inhibitor-1 is a potent and selective janus kinase 3 (JAK3) covalent inhibitor with an IC50 of 11 nM and shows 246-fold selectivity vs other JAKs[1]. JAK3|11 nM (IC50)
[1]. Casimiro-Garcia A, et al. Identification of Cyanamide-Based Janus Kinase 3 (JAK3) Covalent Inhibitors. J Med Chem. 2018 Dec 13;61(23):10665-10699.
Average Rating: 5 (Based on Reviews and 36 reference(s) in Google Scholar.)
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