p32 Inhibitor M36 (Synonyms: M36) |
| Catalog No.GC36833 |
p32 inhibitor M36 (M36) is a p32 mitochondrial protein inhibitor, which binds directly to p32 and inhibits p32 association with LyP-1.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 802555-85-7
Sample solution is provided at 25 µL, 10mM.
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p32 inhibitor M36 (M36) is a p32 mitochondrial protein inhibitor, which binds directly to p32 and inhibits p32 association with LyP-1[1]. p32[1]
p32 Inhibitor M36 inhibits SF188 glioma cells proliferation (IC50 of 77.9 μM in complete media) and is much more potent under low glucose conditions with an IC50 of 7.3 μM[1]. p32 Inhibitor M36 is selective for p32 overexpressing cells[1].p32 Inhibitor M36 is also a potent inhibitor of patient-derived neurospheres with an IC50 of 2.8 μM[1].
[1]. Yenugonda V,et al. A novel small molecule inhibitor of p32 mitochondrial protein overexpressed in glioma. J Transl Med. 2017 Oct 18;15(1):210.
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