Vigabatrin (Synonyms: γ-Vinyl GABA) |
| Catalog No.GC37905 |
Inhibitor of GABA transaminase
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 68506-86-5
Sample solution is provided at 25 µL, 10mM.
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Vigabatrin is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that irreversibly inhibits the catabolism of GABA by GABA transaminase.[1] It produces a dose-dependent increase in extracellular GABA, and has been shown to result in increasing seizure suppression.[2]
Reference:
[1]. Willmore, L.J., Abelson, M.B., Ben-Menachem, E., et al. Vigabatrin: 2008 Update. Epilepsia 50(2), 163-173 (2009).
[2]. Appleton, R.E. The new antiepileptic drugs. Arch. Dis. Child. 75(3), 256-262 (1996).
Average Rating: 5 (Based on Reviews and 35 reference(s) in Google Scholar.)
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