3,4-Dimethylmethcathinone metabolite (hydrochloride) ((±)-Pseudoephedrine stereochemistry) (Synonyms: 3,4DMMC metabolite) |
Catalog No.GC45330 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 4865-62-7
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
3,4-Dimethylmethcathinone (3,4-DMMC) (hydrochloride) ((±)-pseudoephedrine stereochemistry) is a potential designer drug with combined features of amphetamines, cathinones, and phenethylamines. It is structurally related to 4-methylmethcathinone, a psychoactive compound that has been identified in products sold as bath salts and plant food.1,2,3 This metabolite of 3,4-DMMC features conversion of the β-keto group to β-hydroxy and is an enantiomeric mixture of the R,R and S,S orientations at carbons one and two, as in pseudoephedrine. The physiological and toxicological properties of this compound have not been elucidated. This product is intended for research and forensic applications.
References
1. Gibbons, S., and Zloh, M. An analysis of the 'legal high' mephedrone. Bioorg. Med. Chem. Lett. 20(14), 4135-4139 (2010).
2. James, D., Adams, R.D., Spears, R., et al. Clinical characteristics of mephedrone toxicity reported to the UK National Poisons Information Service. Emerg.Med.J. 28, 686-689 (2011).
3. Jankovics, P., VÁradi, A., T•lgyesi, L., et al. Identification and characterization of the new designer drug 4'-methylethcathinone (4-MEC) and elaboration of a novel liquid chromatography-tandem mass spectrometry (LC-MS/MS) screening method for seven different methcathinone analogs. Forensic Science International (2011).
Cas No. | 4865-62-7 | SDF | |
Synonyms | 3,4DMMC metabolite | ||
Canonical SMILES | C[C@@H](NC)[C@H](O)C1=CC(C)=C(C)C=C1.Cl | ||
Formula | C12H19NO.HCl | M.Wt | 229.8 |
Solubility | DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 25 mg/ml,PBS (pH 7.2): 5 mg/ml | Storage | Store at -20°C |
General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. |
Prepare stock solution | |||
1 mg | 5 mg | 10 mg | |
1 mM | 4.3516 mL | 21.7581 mL | 43.5161 mL |
5 mM | 0.8703 mL | 4.3516 mL | 8.7032 mL |
10 mM | 0.4352 mL | 2.1758 mL | 4.3516 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Average Rating: 5
(Based on Reviews and 32 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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