Home>>Analytical Standards>>3,4-Dimethylmethcathinone metabolite (hydrochloride) ((±)-Pseudoephedrine stereochemistry)

3,4-Dimethylmethcathinone metabolite (hydrochloride) ((±)-Pseudoephedrine stereochemistry) (Synonyms: 3,4DMMC metabolite)

Catalog No.GC45330

 

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3,4-Dimethylmethcathinone metabolite (hydrochloride) ((±)-Pseudoephedrine stereochemistry) Chemical Structure

Cas No.: 4865-62-7

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Sample solution is provided at 25 µL, 10mM.

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Background

3,4-Dimethylmethcathinone (3,4-DMMC) (hydrochloride) ((±)-pseudoephedrine stereochemistry) is a potential designer drug with combined features of amphetamines, cathinones, and phenethylamines. It is structurally related to 4-methylmethcathinone, a psychoactive compound that has been identified in products sold as bath salts and plant food.1,2,3 This metabolite of 3,4-DMMC features conversion of the β-keto group to β-hydroxy and is an enantiomeric mixture of the R,R and S,S orientations at carbons one and two, as in pseudoephedrine. The physiological and toxicological properties of this compound have not been elucidated. This product is intended for research and forensic applications.

References
1. Gibbons, S., and Zloh, M. An analysis of the 'legal high' mephedrone. Bioorg. Med. Chem. Lett. 20(14), 4135-4139 (2010).
2. James, D., Adams, R.D., Spears, R., et al. Clinical characteristics of mephedrone toxicity reported to the UK National Poisons Information Service. Emerg.Med.J. 28, 686-689 (2011).
3. Jankovics, P., VÁradi, A., T•lgyesi, L., et al. Identification and characterization of the new designer drug 4'-methylethcathinone (4-MEC) and elaboration of a novel liquid chromatography-tandem mass spectrometry (LC-MS/MS) screening method for seven different methcathinone analogs. Forensic Science International (2011).

Chemical Properties

Cas No. 4865-62-7 SDF
Synonyms 3,4DMMC metabolite
Canonical SMILES C[C@@H](NC)[C@H](O)C1=CC(C)=C(C)C=C1.Cl
Formula C12H19NO.HCl M.Wt 229.8
Solubility DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 25 mg/ml,PBS (pH 7.2): 5 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 4.3516 mL 21.7581 mL 43.5161 mL
5 mM 0.8703 mL 4.3516 mL 8.7032 mL
10 mM 0.4352 mL 2.1758 mL 4.3516 mL
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