Gilvocarcin M (Synonyms: Antibiotic 1072A) |
| Catalog No.GC43755 |
Gilvocarcin M is an antibiotic originally isolated from S.
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Cas No.: 77879-89-1
Sample solution is provided at 25 µL, 10mM.
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Gilvocarcin M is an antibiotic originally isolated from S. gilvotanareus. It is active against S. aureus when used at a concentration of 32 µg/ml. Gilvocarcin M inhibits growth of KB cells (IC50 = 0.52 µg/ml) but has no effect on survival in a P388 mouse model of leukemia when used at doses ranging from 25 to 400 mg/kg. Gilvocarcin M intercalates into bacteriophage PM2 DNA. It is toxic to rats with an intravenous LD50 value of 450 mg/kg.
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)
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