Glucocerebrosides (Gaucher's spleen) (Synonyms: Ganglioside GL1a, Gaucher cerebroside, GluCers (Gaucher's spleen), Glucocerebrosides, Glucosylceramides (Gaucher's spleen)) |
| Catalog No.GC43768 |
Glucocerebrosides are formed by the tethering of glucose to a ceramide by glucosylceramide synthase.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 85305-87-9
Sample solution is provided at 25 µL, 10mM.
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Glucocerebrosides are formed by the tethering of glucose to a ceramide by glucosylceramide synthase. They are present in neuronal and non-neuronal mammalian tissues and are found at low quantities in a large number of plant species. Glucocerebrosides are precursors in the synthesis of lactosylceramides and gangliosides. Increased levels of glucocerebrosides are associated with obesity-induced insulin resistance in mice and with neuronal deficits observed in neuronopathic Gaucher disease. This product is a mixture of glucocerebrosides, with variable ceramide chain lengths, isolated from a spleen of a human with Gaucher's disease.
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