GNE-4997 |
| Catalog No.GC32053 |
GNE-4997 is a potent and selective interleukin-2-inducible T-cell kinase (ITK) inhibitor with a Ki of 0.09 nM, and the correlation between the basicity of solubilizing elements in GNE-4997 and off-target antiproliferative effects reduces cytotoxicity.
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Cas No.: 1705602-02-3
Sample solution is provided at 25 µL, 10mM.
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GNE-4997 is a potent and selective ITK/TSK inhibitor.
[1]. Fauber BP, et al. Discovery of imidazo[1,5-a]pyridines and -pyrimidines as potent and selective RORc inverse agonists. Bioorg Med Chem Lett. 2015 Aug 1;25(15):2907-12.
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