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Home >> Infectious Disease >> Viral Diseases >> HIV

HIV

Products for  HIV

  1. Cat.No. Product Name Information
  2. GC65363 (1R)-Tenofovir amibufenamide (1R)-Tenofovir amibufenamide ((1R)-HS-10234) is the isomer of Tenofovir amibufenamide, is an orally active antiviral agent. (1R)-Tenofovir amibufenamide Chemical Structure
  3. GC64260 (2S,5S)-Censavudine (2S,5S)-Censavudine ((2S,5S)-OBP-601) is the (2S,5S)-enantiomer of Censavudine. (2S,5S)-Censavudine Chemical Structure
  4. GC65085 3'-Azido-3'-deoxy-5-methylcytidine 3'-Azido-3'-deoxy-5-methylcytidine (CS-92) is a potent xenotropic murine leukemia-related retrovirus (XMRV) inhibitor with a CC50 of 43.5 μM in MCF-7 cells. 3'-Azido-3'-deoxy-5-methylcytidine Chemical Structure
  5. GC65963 AzddMeC AzddMeC (CS-92) is an antiviral nucleoside analogue and a potent potent, selective and orally active HIV-1 reverse transcriptase and HIV-1 replication inhibitor. In HIV-1-infected human PBM cells and HIV-1-infected human macrophages, the EC50 values of AzddMeC are 9 nM and 6 nM, respectively. AzddMeC Chemical Structure
  6. GC68449 CA inhibitor 1 CA inhibitor 1 Chemical Structure
  7. GC66051 Cabotegravir sodium Cabotegravir (GSK-1265744) sodium is a orally active and long-acting HIV integrase inhibitor and organic anion transporter 1/3 (OAT1/OAT3) inhibitor with IC50 values of 2.5 nM, 0.41 μM and 0.81 μM for HIVADA, OAT3 and OAT1, respectively. Cabotegravir sodium is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1, with low potential to interact with other antiretroviral drugs (ARVs). Cabotegravir sodium can be used to research AIDS. Cabotegravir sodium Chemical Structure
  8. GC64261 Censavudine Censavudine (OBP-601; BMS-986001), a nucleoside analog, is a nucleoside reverse transcriptase inhibitor. Censavudine Chemical Structure
  9. GC66467 Claficapavir Claficapavir (A1752) is a specific nucleocapsid protein (NC) inhibitor with an IC50 around 1 μM. Claficapavir strongly binds the HIV-1 NC (Kd=20 nM) thereby inhibiting the chaperone properties of NC and leading to good antiviral activity against the HIV-1. Claficapavir Chemical Structure
  10. GC25306 CQ31

    CQ31, a small molecule, selectively activates caspase activation and recruitment domain-containing 8 (CARD8).

     CQ31 Chemical Structure
  11. GC64068 Cyclotriazadisulfonamide Cyclotriazadisulfonamide (CADA) is a specific CD4-targeted HIV entry inhibitors. Cyclotriazadisulfonamide Chemical Structure
  12. GC64391 DDX3-IN-2 DDX3-IN-2 is an active DEADbox polypeptide 3 (DDX3) inhibitor with an IC50 value of 0.3 μM. DDX3-IN-2 Chemical Structure
  13. GC64270 Decanoyl-RVKR-CMK TFA Decanoyl-RVKR-CMK (DecRVKRcmk) TFA inhibits over-expressed gp160 processing and HIV-1 replication. Decanoyl-RVKR-CMK TFA Chemical Structure
  14. GC64484 Emivirine Emivirine (MKC-442) is a non-nucleoside reverse transcriptase inhibitors (NNRTIs) with Ki values of 0.20 and 0.01 μM for dTTP- and dGTP-dependent DNA or RNA polymerase activity, respectively. Emivirine Chemical Structure
  15. GC64233 Gomisin M2 Gomisin M2 ((+)-Gomisin M2) is a lignan isolated from the fruits of Schisandra rubriflora with anti-HIV activity (EC50 of 2.4 μM). Gomisin M2 Chemical Structure
  16. GC68023 HIV-1 inhibitor-48 HIV-1 inhibitor-48 Chemical Structure
  17. GC65256 HIV-1 inhibitor-6 HIV-1 inhibitor-6 (compound 9), a diheteroarylamide-based compound, is a potent HIV-1 pre-mRNA alternative splicing inhibitor. HIV-1 inhibitor-6 Chemical Structure
  18. GC65158 HIV-1 inhibitor-8 HIV-1 inhibitor-8 is an orally active, low-toxicity and potent HIV?1 non-nucleoside reverse transcriptase inhibitor (NNRTI). HIV-1 inhibitor-8 Chemical Structure
  19. GC65134 HIV-IN-6 HIV-IN-6 is a HIV-Ⅰ viral replication inhibitor by targeting Src family kinases (SFK) that interact with Nef protein of the virus, such as Hck. HIV-IN-6 Chemical Structure
  20. GC65034 Ibalizumab Ibalizumab (TMB-355) is a humanised IgG4 monoclonal antibody that prevents HIV cell entry by binding to CD4 receptor. Ibalizumab Chemical Structure
  21. GC65905 NBD-14189 NBD-14189 is a potent HIV-1 entry antagonist with an IC50 of 89 nM against the HIV-1HXB2 pseudovirus. NBD-14189 binds to HIV-1 gp120 and shows potent antiviral activity (EC50<200 nM). NBD-14189 Chemical Structure
  22. GC65903 NBD-14270 NBD-14270, a pyridine analogue, is a potent HIV-1 entry antagonist with an IC50 of 180 nM against 50 HIV-1 Env-pseudotyped viruses. NBD-14270 binds to HIV-1 gp120 and shows potent antiviral activity. NBD-14270 shows low cytotoxicity (CC50>100 μM). NBD-14270 Chemical Structure
  23. GC64331 Ritonavir-13C,d3 Ritonavir-13C,d3 Chemical Structure
  24. GC63979 Ro24-7429 Ro24-7429 is a potent and orally active HIV-1 transactivator protein Tat antagonist. Ro24-7429 Chemical Structure
  25. GC63840 Tat-beclin 1 Tat-beclin 1, a peptide derived from a region of the autophagy protein (beclin 1), is a potent inducer of autophagy and interacts with negative regulator of autophagy, GAPR-1 (GLIPR2). Tat-beclin 1 Chemical Structure
  26. GC64221 Tigloylgomisin P Tigloylgomisin P, a lignin, has anti-HIV activity with an EC50 of 37 μM. Tigloylgomisin P Chemical Structure
  27. GC70056 Trecovirsen

    Trecovirsen (GEM91) is an antisense oligonucleotide that targets the HIV gag gene.

     Trecovirsen Chemical Structure
  28. GC64378 Valproic acid-d6 Valproic acid-d6 (VPA-d6) is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches. Valproic acid-d6 Chemical Structure
  29. GC26066 WAY-383487 WAY-383487 is one of the Tat peptide derivatives and inhibits HIV-1 long terminal repeat-activated transcription. WAY-383487 Chemical Structure

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