1,2-Dimyristoyl-sn-glycero-3-phosphate (sodium salt) (Synonyms: DMPA) |
| カタログ番号GC41806 |
リゾホスファチジン酸のアシル化、ジアシルグリセロールのリン酸化、またはホスファチジルコリンからコリン基を除去することによって、ホスファチジン酸（PAs）が形成される可能性があります。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 80724-31-8
Sample solution is provided at 25 µL, 10mM.
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Phosphatidic acids (PAs) can be formed by the acylation of lysophosphatidic acids, the phosphorylation of diacylglycerols, or the removal of the choline group from phosphatidylcholine.[1] They have important roles in intracellular and extracellular signaling. [2][3] 1,2-Dimyristoyl-sn-glycero-3-phosphate is a phospholipid containing the long-chain (14:0) myristic acid inserted at the sn-1 and sn-2 positions. It may be useful in evaluating the role of PAs in micelles, liposomes, and artificial membranes.
Reference:
[1]. Athenstaedt, K., and Daum, G. Phosphatidic acid, a key intermediate in lipid metabolism. European Journal of Biochemistry 266, 1-16 (1999).
[2]. English, D. Phosphatidic acid: A lipid messenger involved in intracellular and extracellular signalling. Cellular Signalling 8, 341-347 (1996).
[3]. Gomez-Cambronero, J. New concepts in phospholipase D signaling in inflammation and cancer. ScientificWorldJournal 10, 1356-1369 (2010).
| Cas No. | 80724-31-8 | SDF | |
| 同義語 | DMPA | ||
| Chemical Name | 1,2-dimyristoyl-sn-glycero-3-phosphate, monosodium salt | ||
| Canonical SMILES | O=C(CCCCCCCCCCCCC)OC[C@@H](OC(CCCCCCCCCCCCC)=O)COP([O-])(O)=O.[Na+] | ||
| Formula | C31H60O8P•Na | M.Wt | 614.8 |
| 溶解度 | 1.6mg/mL in chloroform | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 1.6265 mL | 8.1327 mL | 16.2655 mL |
| 5 mM | 0.3253 mL | 1.6265 mL | 3.2531 mL |
| 10 mM | 0.1627 mL | 0.8133 mL | 1.6265 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
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μL
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Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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