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17-Epiestriol (Synonyms: 16α-hydroxy-17α-Estradiol, 16α,17α-Estriol, 17α-Estriol, 17-epi-Estriol, NSC 84051)

カタログ番号GC48819

エストロンの代謝物質

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17-Epiestriol 化学構造

Cas No.: 1228-72-4

サイズ 価格 在庫数 個数
1mg
$163.00
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5mg
$733.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

17-エピエストリオールは、エストロンの代謝物です。1 これは、C-17ケトンの還元による16α-ヒドロキシエストロン中間体からエストロンを介して形成されます。 17-エピエストリオールは、17β-エストラジオールに比べて、雌性ホルモン受容体α(ERα)およびERβに対する相対的な結合親和力が29および80であることが示されています。2

1.ブリントン、L.A.、トラバート、B.、アンダーソン、G.L.、他。血清エストロゲンおよびエストロゲン代謝物と閉経後女性における子宮内膜がんリスク。Cancer Epidemiol.Biomarkers Prev.25(7)1081-1089(2016) 2.Kuiper, G.G.J.M., Lemmen, J.G., Carlsson, B., 他。エストロゲン受容体βとのエストロゲン化学物質および植物性エストロゲンの相互作用。Endocrinology139(10)4252-4263(1998)

Chemical Properties

Cas No. 1228-72-4 SDF
同義語 16α-hydroxy-17α-Estradiol, 16α,17α-Estriol, 17α-Estriol, 17-epi-Estriol, NSC 84051
Canonical SMILES C[C@@]12[C@](C[C@H]([C@H]2O)O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC=C(O)C=C4CC3
Formula C18H24O3 M.Wt 288.4
溶解度 Methanol: slightly soluble Storage -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 3.4674 mL 17.337 mL 34.6741 mL
5 mM 0.6935 mL 3.4674 mL 6.9348 mL
10 mM 0.3467 mL 1.7337 mL 3.4674 mL
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