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(±)7(8)-EpDPA (Synonyms: (±)7,8-EDP, (±)7,8-EpDPE, (±)7,8-epoxy DPA, (±)7,8-epoxy Docosapentaenoic Acid)

カタログ番号GC41203

ドコサヘキサエン酸は、特に脳と網膜で神経組織中で最も豊富なω-3脂肪酸です。

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(±)7(8)-EpDPA 化学構造

Cas No.: 895127-66-9

サイズ 価格 在庫数 個数
25μg
$57.00
在庫あり
50μg
$108.00
在庫あり
100μg
$204.00
在庫あり
500μg
$904.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

ドコサヘキサエン酸は、神経組織、特に脳と網膜で最も豊富なω-3脂肪酸です。(±)7(8)-EpDPAは、シトクロムP450エポキシゲナーゼの作用によって生成されるDHAのエポキシ誘導体です。血漿や脳・脊髄組織中に自然発生し、ω-3脂肪酸の摂取後に増加します。(±)7(8)-EpDPAおよび他のDHAのエポキシ代謝物は受容体やチャネル活性を調節して多様な効果を引き起こし、血管拡張を促進したり、血管新生を抑制したり、炎症や神経障害性疼痛を減少させたりします。(±)7(8)-EpDPAは可溶性エポキシヒドロラーゼ(KM = 15 µM)の基質であり、それによって対応するジオールに変換されます。

Chemical Properties

Cas No. 895127-66-9 SDF
同義語 (±)7,8-EDP, (±)7,8-EpDPE, (±)7,8-epoxy DPA, (±)7,8-epoxy Docosapentaenoic Acid
Canonical SMILES CC/C=C\C/C=C\C/C=C\C/C=C\C[C@@H](O1)[C@@H]1C/C=C\CCC(O)=O
Formula C22H32O3 M.Wt 344.5
溶解度 DMF: 50 mg/ml,DMSO: 50 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): 1 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 2.9028 mL 14.5138 mL 29.0276 mL
5 mM 0.5806 mL 2.9028 mL 5.8055 mL
10 mM 0.2903 mL 1.4514 mL 2.9028 mL
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レビュー

Review for (±)7(8)-EpDPA

Average Rating: 5 ★★★★★ (Based on Reviews and 21 reference(s) in Google Scholar.)

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