(±)-Epinephrine (hydrochloride) (Synonyms: (±)-Adrenaline, DL-Adrenaline, DL-Epinephrine) |
| カタログ番号GC41670 |
(±)-エピネフリンは、副腎髄質から放出される天然の神経伝達物質であり、アドレノ受容体を活性化します（α1A-、β2-、およびβ1-アドレナリン受容体に対するKisはそれぞれ15,735、3,970 nMです）。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 329-63-5
Sample solution is provided at 25 µL, 10mM.
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(±)-Epinephrine is a natural neurotransmitter that is released from the adrenal medulla and activates adrenoceptors (Kis = 15, 735, and 3,970 nM for α1A-, β2-, and β1-adrenergic receptors, respectively). Through these receptors, (±)-epinephrine may induce either contraction or relaxation of vascular smooth muscle, depending on adrenoceptor subtype expression. Receptor-mediated actions of (±)-epinephrine are also relevant to blocking anaphylaxis, reversing cardiac arrest, and reducing bleeding in clinical trials.
| Cas No. | 329-63-5 | SDF | |
| 同義語 | (±)-Adrenaline, DL-Adrenaline, DL-Epinephrine | ||
| Canonical SMILES | OC1=C(O)C=CC(C(O)CNC)=C1.Cl | ||
| Formula | C9H13NO3•HCl | M.Wt | 219.7 |
| 溶解度 | DMF: 20 mg/ml,DMSO: 20 mg/ml,PBS (pH 7.2): 5 mg/ml | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 4.5517 mL | 22.7583 mL | 45.5166 mL |
| 5 mM | 0.9103 mL | 4.5517 mL | 9.1033 mL |
| 10 mM | 0.4552 mL | 2.2758 mL | 4.5517 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 40 reference(s) in Google Scholar.)
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