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(±)-Nornicotine (Synonyms: DL-Nornicotine, (R,S)-Nornicotine)

カタログ番号GC41676

(±)-ノルニコチンは、神経ニコチン性アセチルコリン受容体(nAChR)アゴニストとして作用するニコチンの代謝物です。

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(±)-Nornicotine 化学構造

Cas No.: 5746-86-1

サイズ 価格 在庫数 個数
50mg
$32.00
在庫あり
100mg
$47.00
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250mg
$142.00
在庫あり
500mg
$268.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

(±)?ノルニコチンは、神経ニコチン性アセチルコリン受容体(nAChR)アゴニストとして作用するニコチンの代謝物です。α6およびα7サブユニットを含む神経nAChRは、Xenopus oocytesで発現した場合、約4および17 µMのEC50値で特にノルニコチンに反応します。ノルニコチンは内皮細胞株において細胞移動を促進し、細胞間接着点を不安定化させます。一般的に乱用の可能性がないと考えられていますが、ラットによって自己投与されたことがあります。尿中でも検出されることがあります。

Chemical Properties

Cas No. 5746-86-1 SDF
同義語 DL-Nornicotine, (R,S)-Nornicotine
Canonical SMILES C1(C2CCCN2)=CC=CN=C1
Formula C9H12N2 M.Wt 148.2
溶解度 DMF: 50 mg/ml,DMSO: 30 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): 1 mg/ml Storage Store at 2-8°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 6.7476 mL 33.7382 mL 67.4764 mL
5 mM 1.3495 mL 6.7476 mL 13.4953 mL
10 mM 0.6748 mL 3.3738 mL 6.7476 mL
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Average Rating: 5 ★★★★★ (Based on Reviews and 34 reference(s) in Google Scholar.)

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