ホーム>>Signaling Pathways>> Cancer Biology>>2,3,4-Tri-O-acetyl-β-D-Glucuronide methyl ester

2,3,4-Tri-O-acetyl-β-D-Glucuronide methyl ester

カタログ番号GC46510

合成中間体

Products are for research use only. Not for human use. We do not sell to patients.

2,3,4-Tri-O-acetyl-β-D-Glucuronide methyl ester 化学構造

Cas No.: 73464-50-3

サイズ 価格 在庫数 個数
100 mg
$117.00
在庫あり
250 mg
$251.00
在庫あり
500 mg
$473.00
在庫あり
1 g
$887.00
在庫あり

Tel:(909) 407-4943 Email: sales@glpbio.com

顧客レビュー

カスタマーレビューに基づきます。

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

    Bioactive Compounds Premium Provider

Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

View current batch:

Background

2,3,4-トリ-O-アセチル-β-D-グルクロン酸メチルエステルは、抗腫瘍抗生物質ダウノマイシンのプロドラッグ形式の合成における合成中間体です。1

1. Leenders, R.G.G.、およびScheeren, H.W.による新規ダウノマイシン-リン酸-硫酸塩-β-グルクロニドおよび-β-グルコシドプロドラッグの合成と評価、ADEPT応用のためのBioorg。Med。Chem。Lett。5(24)2975-2980(1995年)

Chemical Properties

Cas No. 73464-50-3 SDF
Canonical SMILES O=C(C)O[C@@H]1[C@@H](C(OC)=O)O[C@@H](O)[C@H](OC(C)=O)[C@H]1OC(C)=O
Formula C13H18O10 M.Wt 334.3
溶解度 DMF: 15mg/mL,DMSO: 10mg/mL,Ethanol: 15mg/mL,PBS (pH 7.2): 2mg/mL Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.9913 mL 14.9566 mL 29.9133 mL
5 mM 0.5983 mL 2.9913 mL 5.9827 mL
10 mM 0.2991 mL 1.4957 mL 2.9913 mL
  • モルアリティ計算機

  • 希釈計算機

質量
=
濃度
x
容積
x
MW*
 
 
 
**ストックソリューションを準備する際には、常にバイアルラベルおよび MSDS/CoA(オンラインで利用可能)で掲載された製品のロット固有分子量を使用してください。

計算

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

レビュー

Review for 2,3,4-Tri-O-acetyl-β-D-Glucuronide methyl ester

Average Rating: 5 ★★★★★ (Based on Reviews and 5 reference(s) in Google Scholar.)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%
Review for 2,3,4-Tri-O-acetyl-β-D-Glucuronide methyl ester

GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.

Required fields are marked with *

You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.