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2-bromo 17β-Estradiol (Synonyms: 2-bromo E2, 2-bromo β-Estradiol, 2-bromo Estradiol, NSC 105460, 2-bromo 17β-Oestradiol)

カタログ番号GC49609

合成ステロイドであり、エストロゲン2-ヒドロキシラーゼの阻害剤です。

Products are for research use only. Not for human use. We do not sell to patients.

2-bromo 17β-Estradiol 化学構造

Cas No.: 15833-07-5

サイズ 価格 在庫数 個数
5 mg
$40.00
在庫あり
10 mg
$76.00
在庫あり
25 mg
$179.00
在庫あり
50 mg
$338.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

2-ブロモ17β-エストラジオールは、合成ステロイドであり、エストロゲン2-ヒドロキシラーゼの阻害剤です。1 50および100μMの濃度で使用された場合に、ラット肝微粒子中のエストロゲン2-ヒドロキシラーゼを阻害します。 2-ブロモ17β-エストラジオール(5mg / kg)は、マウスにおけるアポモルフィン誘発性クライミング行動の抑制を防止することが報告されています。2

1. Brueggemeier, R.W. エストロゲン2-ヒドロキシラーゼの阻害。J. ステロイドバイオケミストリー19(5)1683-1685(1983) 2. Fung, Y.K.、Stevens, J.M.、Palmer, C.W.Jr。などによるブロモエストロゲンによるエストラジオールのアポモルフィン誘発クライミング行動への影響の抑制。ステロイド49(4-5)287-294(1987)

Chemical Properties

Cas No. 15833-07-5 SDF Download SDF
同義語 2-bromo E2, 2-bromo β-Estradiol, 2-bromo Estradiol, NSC 105460, 2-bromo 17β-Oestradiol
Canonical SMILES C[C@@]12[C@](CC[C@@H]2O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC(Br)=C(O)C=C4CC3
Formula C18H23BrO2 M.Wt 351.3
溶解度 DMSO: soluble,Methanol: soluble Storage -20°C, protect from light
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 2.8466 mL 14.2328 mL 28.4657 mL
5 mM 0.5693 mL 2.8466 mL 5.6931 mL
10 mM 0.2847 mL 1.4233 mL 2.8466 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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レビュー

Review for 2-bromo 17β-Estradiol

Average Rating: 5 ★★★★★ (Based on Reviews and 39 reference(s) in Google Scholar.)

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