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2-NP-AOZ (Synonyms: NPAOZ)

カタログ番号GC49786

2-NP-AOZ は、AOZ の 2-ニトロフェニル誘導体です。

Products are for research use only. Not for human use. We do not sell to patients.

2-NP-AOZ 化学構造

Cas No.: 19687-73-1

サイズ 価格 在庫数 個数
1 mg
$40.00
在庫あり
5 mg
$149.00
在庫あり
10 mg
$219.00
在庫あり
25 mg
$496.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description of 2-NP-AOZ

2-NP-AOZ is a derivatized metabolite of the nitrofuran antiprotozoal and antibacterial agent furazolidone .1 It is formed from the tissue-bound furazolidone metabolite 3-amino-2-oxazolidinone (AOZ) after acid hydrolysis and derivatization with o-nitrobenzaldehyde (o-NBA). 2-NP-AOZ has been used as a marker of furazolidone use in pigs.2

1.Hoogenboom, L.A., Berghmans, T.H., Polman, T.H., et al.Depletion of protein-bound furazolidone metabolites containing the 3-amino-2-oxazolidinone side-chain from liver, kidney and muscle tissues from pigsFood Addit. Contam.9(6)623-630(1992)

Chemical Properties of 2-NP-AOZ

Cas No. 19687-73-1 SDF
同義語 NPAOZ
Canonical SMILES O=C1OCCN1/N=C/C2=C([N+]([O-])=O)C=CC=C2
Formula C10H9N3O4 M.Wt 235.2
溶解度 Chloroform: slightly soluble,Methanol: slightly soluble Storage -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of 2-NP-AOZ

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 4.2517 mL 21.2585 mL 42.517 mL
5 mM 0.8503 mL 4.2517 mL 8.5034 mL
10 mM 0.4252 mL 2.1259 mL 4.2517 mL
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計算

In vivo Formulation Calculator (Clear solution) of 2-NP-AOZ

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 23 reference(s) in Google Scholar.)

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