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(2'S)-Nicotine-1-oxide (Synonyms: Nicotine-N-oxide)

カタログ番号GC18622

(2'S)-ニコチン-1-オキシドは、ニコチンの代謝物です。

Products are for research use only. Not for human use. We do not sell to patients.

(2'S)-Nicotine-1-oxide 化学構造

Cas No.: 2820-55-5

サイズ 価格 在庫数 個数
1mg
$52.00
在庫あり
5mg
$226.00
在庫あり
10mg
$398.00
在庫あり
25mg
$872.00
在庫あり

Tel:(909) 407-4943 Email: sales@glpbio.com

顧客レビュー

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

(2'S)-ニコチン-1-オキシドは、ニコチンの代謝物です。肝臓でシトクロムP450(CYP)アイソフォームCYP2A6によってニコチンが代謝されると形成されます。(2'S)-ニコチン-1-オキシドは、人間の精子や精液中でも検出されています。

Chemical Properties

Cas No. 2820-55-5 SDF
同義語 Nicotine-N-oxide
Chemical Name 3-[(2S)-1-methyl-2-pyrrolidinyl]-pyridine 1-oxide
Canonical SMILES CN1CCC[C@H]1C2=C[N+]([O-])=CC=C2
Formula C10H14N2O M.Wt 178.2
溶解度 DMF: 50 mg/mL,DMSO: 30 mg/mL,Ethanol: 50 mg/mL,PBS (pH 7.2): 1 mg/mL Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 5.6117 mL 28.0584 mL 56.1167 mL
5 mM 1.1223 mL 5.6117 mL 11.2233 mL
10 mM 0.5612 mL 2.8058 mL 5.6117 mL
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計算

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

レビュー

Review for (2'S)-Nicotine-1-oxide

Average Rating: 5 ★★★★★ (Based on Reviews and 38 reference(s) in Google Scholar.)

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