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2-Thenoyltrifluoroacetone (Synonyms: NSC 66544, NSC 405702, NSC 405703, NSC 405704, NSC 405705, NSC 405706, TTFA)

カタログ番号GC42193

2-テノイルトリフルオロアセトンはキレート剤です。

Products are for research use only. Not for human use. We do not sell to patients.

2-Thenoyltrifluoroacetone 化学構造

Cas No.: 326-91-0

サイズ 価格 在庫数 個数
10g
$22.00
在庫あり
25g
$41.00
在庫あり
50g
$72.00
在庫あり
100g
$109.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description of 2-Thenoyltrifluoroacetone

2-Thenoyltrifluoroacetone (TTFA) is an inhibitor of respiration in animals and bacteria. In animals, TTFA binds at the quinone reduction site of succinate:ubiquinone oxidoreductase (SQR; Complex II), preventing ubiquinone from binding. It inhibits NADH fumarate reductase in bacteria. TTFA also inhibits photosystem II in plants and NADH-ubiquinone oxidoreductase of the virus Vibrio cholerae, decreasing cholera toxin production. This compound is also a chelator of metals, including lanthanum, zirconium, hafnium, and neodymium.

Chemical Properties of 2-Thenoyltrifluoroacetone

Cas No. 326-91-0 SDF
同義語 NSC 66544, NSC 405702, NSC 405703, NSC 405704, NSC 405705, NSC 405706, TTFA
Canonical SMILES O=C(C1=CC=CS1)CC(C(F)(F)F)=O
Formula C8H5F3O2S M.Wt 222.2
溶解度 DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of 2-Thenoyltrifluoroacetone

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 4.5005 mL 22.5023 mL 45.0045 mL
5 mM 0.9001 mL 4.5005 mL 9.0009 mL
10 mM 0.45 mL 2.2502 mL 4.5005 mL
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計算

In vivo Formulation Calculator (Clear solution) of 2-Thenoyltrifluoroacetone

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Average Rating: 5 ★★★★★ (Based on Reviews and 11 reference(s) in Google Scholar.)

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