3,6-diacetoxy Phthalonitrile (Synonyms: ADB, 1,4-Diacetoxy-2,3-dicyanobenzene, 2,3-Dicyano-1,4-hydroquinone diacetate) |
| カタログ番号GC42239 |
3,6-ジアセトキシ フタロニトリルは、細胞透過性蛍光プローブです。
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Cas No.: 83619-73-2
Sample solution is provided at 25 µL, 10mM.
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3,6-diacetoxy Phthalonitrile is a fluorescent probe for monitoring intracellular pH by flow cytometry in living cells. It rapidly crosses cell membranes and is cleaved by cytosolic esterases to form the fluorescent pH indicator 2,3-dicyano-hydroquinone (DCH), which is excited at UV wavelengths. DCH can be excited at 351 nm, with pH-dependent emission in the range of 450-476 nm (pH 5.0-10.0) using a potassium-based buffer.
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