(3R,4R)-A2-32-01 |
カタログ番号GC39179 |
(3R,4R)-A2-32-01 (化合物 24(R,R))、A2-32-01 の (R,R)-エナンチオマーは、黄色ブドウ球菌のカゼイン分解プロテアーゼ (SaClpP) 阻害剤です 。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1359752-95-6
Sample solution is provided at 25 µL, 10mM.
(3R,4R)-A2-32-01 (compound 2), an anti-virulence drug, is a specific caseinolytic protein proteases (ClpP) inhibitor with an EC50 of 4.5 μM, and shows a tolerable cytotoxicity[1].
[1]. Zeiler E, et al. Development and characterization of improved β-lactone-based anti-virulence drugs targetingClpP. Bioorg Med Chem. 2012 Jan 15;20(2):583-91.
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