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5-Fluoropentyl-3-pyridinoylindole (hydrochloride)

カタログ番号GC42543

5-フルオロペンチル-3-ピリジノイルインドールは、JWH 018のような強力なCBと同様にアミノペンチルインドール構造を共有する合成カンナビノイド(CB)です。

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5-Fluoropentyl-3-pyridinoylindole (hydrochloride) 化学構造

Cas No.: 2365471-19-6

サイズ 価格 在庫数 個数
1mg
$113.00
在庫あり
5mg
$498.00
在庫あり
10mg
$885.00
在庫あり

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顧客レビュー

カスタマーレビューに基づきます。

Sample solution is provided at 25 µL, 10mM.

Description of 5-Fluoropentyl-3-pyridinoylindole (hydrochloride)

5-Fluoropentyl-3-pyridinoylindole is a synthetic cannabinoid (CB) which shares the aminopentylindole structure of potent CBs like JWH 018 . This compound has a novel pyridinoyl group replacing the more common naphthoyl group found in WIN 55,212-2 and related JWH compounds. It also contains an alkyl-terminal fluoro group, which commonly enhances binding to both the central CB1 and peripheral CB2 receptor. [1] The physiological and toxicological properties of this compound are not known, although it has been detected in herbal mixtures.[2]  This product is intended for forensic and research applications.

Reference:
[1]. Makriyannis, A., and Deng, H. Cannabimimetic indole derivatives. PCT/US00/28832, (2001).
[2]. Uchiyama, N., Kawamura, M., Kikura-Hanajiri, R., et al. URB-754: A new class of designer drug and 12 synthetic cannabinoids detected in illegal products. Forensic Science International 227(1-3), 21-32 (2013).

Chemical Properties of 5-Fluoropentyl-3-pyridinoylindole (hydrochloride)

Cas No. 2365471-19-6 SDF
Chemical Name (1-(5-fluoropentyl)-1H-indol-3-yl)(pyridin-3-yl)methanone, monohydrochloride
Canonical SMILES O=C(C1=CC=CN=C1)C2=CN(CCCCCF)C3=C2C=CC=C3.Cl
Formula C19H19FN2O•HCl M.Wt 346.8
溶解度 0.3mg/mL in ethanol, 10mg/mL in DMSO, or in DMF Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of 5-Fluoropentyl-3-pyridinoylindole (hydrochloride)

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.8835 mL 14.4175 mL 28.8351 mL
5 mM 576.7 μL 2.8835 mL 5.767 mL
10 mM 288.4 μL 1.4418 mL 2.8835 mL
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In vivo Formulation Calculator (Clear solution) of 5-Fluoropentyl-3-pyridinoylindole (hydrochloride)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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