5-Fluoropentyl-3-pyridinoylindole (hydrochloride) |
| カタログ番号GC42543 |
5-フルオロペンチル-3-ピリジノイルインドールは、JWH 018のような強力なCBと同様にアミノペンチルインドール構造を共有する合成カンナビノイド(CB)です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2365471-19-6
Sample solution is provided at 25 µL, 10mM.
5-Fluoropentyl-3-pyridinoylindole is a synthetic cannabinoid (CB) which shares the aminopentylindole structure of potent CBs like JWH 018 . This compound has a novel pyridinoyl group replacing the more common naphthoyl group found in WIN 55,212-2 and related JWH compounds. It also contains an alkyl-terminal fluoro group, which commonly enhances binding to both the central CB1 and peripheral CB2 receptor. [1] The physiological and toxicological properties of this compound are not known, although it has been detected in herbal mixtures.[2] This product is intended for forensic and research applications.
Reference:
[1]. Makriyannis, A., and Deng, H. Cannabimimetic indole derivatives. PCT/US00/28832, (2001).
[2]. Uchiyama, N., Kawamura, M., Kikura-Hanajiri, R., et al. URB-754: A new class of designer drug and 12 synthetic cannabinoids detected in illegal products. Forensic Science International 227(1-3), 21-32 (2013).
| Cas No. | 2365471-19-6 | SDF | |
| Chemical Name | (1-(5-fluoropentyl)-1H-indol-3-yl)(pyridin-3-yl)methanone, monohydrochloride | ||
| Canonical SMILES | O=C(C1=CC=CN=C1)C2=CN(CCCCCF)C3=C2C=CC=C3.Cl | ||
| Formula | C19H19FN2O•HCl | M.Wt | 346.8 |
| 溶解度 | 0.3mg/mL in ethanol, 10mg/mL in DMSO, or in DMF | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 2.8835 mL | 14.4175 mL | 28.8351 mL |
| 5 mM | 576.7 μL | 2.8835 mL | 5.767 mL |
| 10 mM | 288.4 μL | 1.4418 mL | 2.8835 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 36 reference(s) in Google Scholar.)
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