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6-NBDG (Synonyms: 6-NBD-Glucose)

カタログ番号GC18870

6-NBDG は蛍光グルコース類似体であり、蛍光イメージングやグルコースの輸送と取り込みのモニタリングに使用できます。

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6-NBDG 化学構造

Cas No.: 108708-22-1

サイズ 価格 在庫数 個数
500μg
$108.00
在庫あり
1mg
$170.00
在庫あり
5mg
$745.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

6-NBDG is a non-hydrolyzable fluorescent glucose analog that is used to monitor glucose uptake and transport in living cells. 6-NBDG has been validated as a probe for the glucose transporter GLUT1 in cells. The fluorophore NBD displays excitation/emission maxima of 465/535 nm.

References:

1. Hansen, T.V.A., Hansen, M., Nejsum, P., et al. Glucose absorption by the bacillary band of Trichuris muris PLoS Negl. Trop. Dis. 10(9), e0004971 (2016).
2. Wang, M.S., Luo, Z., and Nitin, N. Rapid assessment of drug response in cancer cells using microwell array and molecular imaging Anal. Bioanal. Chem. 406(17), 4195-4206 (2014).
3. Zaman, R.T., Kosuge, H., Pratx, G., et al. Fiber-optic system for dual-modality imaging of glucose probes 18F-FDG and 6-NBDG in atherosclerotic plaques PLoS One 9(9), e108108 (2014).
4. Barros, L.F., Bittner, C.X., Loaiza, A., et al. Kinetic validation of 6-NBDG as a probe for the glucose transporter GLUT1 in astrocytes J. Neurochem. 109(Suppl 1), 94-100 (2009).

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