(6R)-FR054 |
| カタログ番号GC60398 |
(6R)-FR054 は、FR054 の活性の低い異性体です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 10378-06-0
Sample solution is provided at 25 µL, 10mM.
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(6R)-FR054 is an active isomer of FR054. FR054 is an inhibitor of the HBP enzyme PGM3, with a remarkable anti-breast cancer effect. FR054induces endoplasmic reticulum (ER) stress and a ROS-dependent apoptosis[1].
[1]. Francesca Ricciardiello, et al. Inhibition of the Hexosamine Biosynthetic Pathway by Targeting PGM3 Causes Breast Cancer Growth Arrest and Apoptosis. Cell Death Dis. 2018 Mar 7;9(3):377.
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