8-methyl Nonanoic Acid (Synonyms: Isocapric Acid) |
| カタログ番号GC40759 |
カプサイシンは、唐辛子のスパイシーでホットな味を与える化学物質であり、Capsicum科に属する植物の果実によって生産されます。
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Cas No.: 5963-14-4
Sample solution is provided at 25 µL, 10mM.
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Capsaicin, the chemical that imparts the spicy-hot quality of chili peppers, is produced by the fruits of plants belonging to the Capsicum family. 8-methyl Nonanoic acid is an immediate precursor of capsaicin as well as a by-product of capsaicin degradation.[1] Addition of 5 mM of 8-methyl nonanoic acid significantly increases the yield of capsaicin in both immobilized and freely suspended cells of C. frutescens. [2] Capsaicin has reported antimicrobial properties, however isocapric acid can act as a growth substrate in certain bacterial strains.[3]
Reference:
[1]. Kaga, H., Miura, M., and Orito, K. A facile procedure for synthesis of capsaicin. The Journal of Organic Chemistry 54, 3477-3478 (1989).
[2]. Lindsey, K., and Yeoman, M.M. The synthetic potential of immobilised cells of Capsicum frutescens mill cv. annuum. Planta 162, 495-501 (1984).
[3]. Flagan, S.F., and Leadbetter, J.R. Utilization of capsaicin and vanillylamine as growth substrates by Capsicum (hot pepper)-associated bacteria. Environmental Microbiology 8(3), 560-565 (2006).
| Cas No. | 5963-14-4 | SDF | |
| 同義語 | Isocapric Acid | ||
| Chemical Name | 8-methyl Nonanoic Acid | ||
| Canonical SMILES | CC(C)CCCCCCC(=O)O | ||
| Formula | C10H20O2 | M.Wt | 172.3 |
| 溶解度 | 10mg/mL in ethanol, 10mg/mL in DMSO, 10mg/mL in DMF | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
||
| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 5.8038 mL | 29.0192 mL | 58.0383 mL |
| 5 mM | 1.1608 mL | 5.8038 mL | 11.6077 mL |
| 10 mM | 580.4 μL | 2.9019 mL | 5.8038 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 33 reference(s) in Google Scholar.)
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