9-Deazaguanine (Synonyms: NSC 344522) |
カタログ番号GC42644 |
9-デアザグアニンは、プリンヌクレオシドホスホリラーゼ(PNP; Kd = 160 nM)の阻害剤として作用するグアニンの類似体です。
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Cas No.: 65996-58-9
Sample solution is provided at 25 µL, 10mM.
9-Deazaguanine is an analog of guanine that acts as an inhibitor of purine nucleoside phosphorylase (PNP; Kd = 160 nM). Inhibitors of PNP are used to control T cell proliferation, particularly in T cell cancers, autoimmune diseases, and tissue transplant rejection.
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(Based on Reviews and 14 reference(s) in Google Scholar.)Review for 9-Deazaguanine
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