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α-NETA

カタログ番号GC45213

α-NETA は強力で非競合的なコリン アセチルトランスフェラーゼ (ChA; IC50=76 μM) およびコリンエステラーゼ (ChE; IC50=40 μM) 阻害剤です。 α-NETA はアセチルコリンエステラーゼを弱く阻害します (AChE; IC50=1 mM)。

Products are for research use only. Not for human use. We do not sell to patients.

α-NETA 化学構造

Cas No.: 31059-54-8

サイズ 価格 在庫数 個数
5mg
$53.00
在庫あり
25mg
$198.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Product has been cited by 1 publications

Description Chemical Properties Product Documents Related Products

Choline acetyltransferase (ChAT) mediates the synthesis of the neurotransmitter acetylcholine from acetyl-CoA and choline. In addition to its critical role in neurosignaling, deficiencies in ChAT are linked to congenital myasthenic syndromes, Alzheimer's disease, and multiple sclerosis. α-NETA is a stable, non-competitive, and slowly reversible inhibitor of ChAT (IC50 = 9 μM). This naturally fluorescent compound is a poor inhibitor of cholinesterases and carnitine acetyltransferase. α-NETA is commonly used in cells in culture.

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Average Rating: 5 ★★★★★ (Based on Reviews and 19 reference(s) in Google Scholar.)

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