Angoline hydrochloride |
| カタログ番号GC60586 |
アンゴリン塩酸塩は、強力かつ選択的な IL6/STAT3 シグナル伝達経路阻害剤であり、IC50 は 11.56 μM です。アンゴリン塩酸塩は、STAT3 のリン酸化とその標的遺伝子の発現を阻害し、がん細胞の増殖を阻害します。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1071676-04-4
Sample solution is provided at 25 µL, 10mM.
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Angoline hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor with an IC50 of 11.56 μM. Angoline hydrochloride inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation[1].
[1]. Jiawei Liu, et al. Angoline: a selective IL-6/STAT3 signaling pathway inhibitor isolated from Zanthoxylum nitidum. Phytomedicine. Jul-Aug 2014;21(8-9):1088-91.
Average Rating: 5 (Based on Reviews and 12 reference(s) in Google Scholar.)
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