B-Raf IN 10 |
| カタログ番号GC65978 |
B-Raf IN 10 (化合物 C09) は、IC50 が 50 ～ 100 nM の BRAF 阻害剤です。 B-Raf IN 10 は抗腫瘍活性を示します。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1425485-87-5
Sample solution is provided at 25 µL, 10mM.
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B-Raf IN 10 (Compound C09) is a BRAF inhibitor with an IC50 between 50 and 100 nM. B-Raf IN 10 shows antitumor activity[1].
B-Raf IN 10 (Compound C09) (1 μM) shows more than 89% inhibition against BRAF and BRAF V600E[1].
B-Raf IN 10 shows an IC50 between 50 and 100 nM against BRAF, less than 50 nM against BRAF V600E[1].
B-Raf IN 10 (72 h) inhibits A375 and SK-MEL-28 cells growth but not CHL-1 and SK-MEL-31 cells[1].
Cell Viability Assay[1]
| Cell Line: | A375, SK-MEL-28, SK-MEL-31 and CHL-1 |
| Concentration: | |
| Incubation Time: | 72 h |
| Result: | Showed inhibition with IC50s less than 500 nM against A375 and SK-MEL-28 cells, and showed no inhibition against CHL-1 and SK-MEL-31. |
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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