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Butantrone (Synonyms: Butantrone; CCRIS2041; CCRIS-2041; CCRIS 2041)

カタログ番号GB62215

ブタントロンは、ジトラノールの10-ブチリル誘導体であり、抗乾癬作用を持っています。

Products are for research use only. Not for human use. We do not sell to patients.

Butantrone 化学構造

Cas No.: 75464-11-8

サイズ 価格 在庫数 個数
5mg
$250.00
在庫あり
10mg
$450.00
在庫あり
25mg
$950.00
在庫あり
50mg
$1,650.00
在庫あり
100mg
$2,950.00
在庫あり

Tel:(909) 407-4943 Email: sales@glpbio.com


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  • GlpBio Citations

    GlpBio Citations
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Sample solution is provided at 25 µL, 10mM.

Description of Butantrone

Butantrone is the 10-butyryl derivative of dithranol with antipsoriatic activity. When butantrone and dithranol were used in equimolar gradually increasing concentrations in short-contact therapy for psoriasis the efficacy of butantrone was somewhat lower compared to dithranol. Butantrone has an antipsoriatic activity almost equal to that of dithranol. When short contact treatment is used, erythema and staining with butantrone are weaker than with dithranol.

Chemical Properties of Butantrone

Cas No. 75464-11-8 SDF
同義語 Butantrone; CCRIS2041; CCRIS-2041; CCRIS 2041
Canonical SMILES O=C1C2=C(C=CC=C2O)C(C(CCC)=O)C3=CC=CC(O)=C13
Formula C18H16O4 M.Wt 296.322
溶解度 To be determined Storage Store at-20℃
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Butantrone

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.3747 mL 16.8735 mL 33.7471 mL
5 mM 0.6749 mL 3.3747 mL 6.7494 mL
10 mM 0.3375 mL 1.6874 mL 3.3747 mL
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**ストックソリューションを準備する際には、常にバイアルラベルおよび MSDS/CoA(オンラインで利用可能)で掲載された製品のロット固有分子量を使用してください。

計算

In vivo Formulation Calculator (Clear solution) of Butantrone

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for Butantrone

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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